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- NCIT_C1777 IAO_0000115 "A bicyclam with hematopoietic stem cell-mobilizing activity. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation." @default.
- NCIT_C1777 NCIT_A7 NCIT_C17789 @default.
- NCIT_C1777 NCIT_NHC0 "C1777" @default.
- NCIT_C1777 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1777 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1777 NCIT_P107 "Plerixafor" @default.
- NCIT_C1777 NCIT_P108 "Plerixafor" @default.
- NCIT_C1777 NCIT_P207 "C0257001" @default.
- NCIT_C1777 NCIT_P210 "110078-46-1" @default.
- NCIT_C1777 NCIT_P302 "Hematopoietic Stem Cell Mobilization" @default.
- NCIT_C1777 NCIT_P319 "S915P5499N" @default.
- NCIT_C1777 NCIT_P322 "CTRP" @default.
- NCIT_C1777 NCIT_P322 "FDA" @default.
- NCIT_C1777 NCIT_P322 "PCDC" @default.
- NCIT_C1777 NCIT_P325 "A drug used before autologous stem cell transplantation in patients with non-Hodgkin lymphoma or multiple myeloma. Plerixafor is given together with granulocyte-colony stimulating factor (G-CSF) to help move stem cells from the bone marrow to the blood. The stem cells can then be collected, stored, and given back to the patient. Plerixafor is a type of chemokine receptor antagonist." @default.
- NCIT_C1777 NCIT_P329 "410786" @default.
- NCIT_C1777 NCIT_P330 "410786" @default.
- NCIT_C1777 NCIT_P350 "C28H54N8" @default.
- NCIT_C1777 NCIT_P366 "AMD3100" @default.
- NCIT_C1777 NCIT_P399 "410786" @default.
- NCIT_C1777 normalizedInformationContent "100" @default.
- NCIT_C1777 referenceCount "1" @default.
- NCIT_C1777 hasExactSynonym "1,1'-[1,4-Phenylenebis(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane" @default.
- NCIT_C1777 hasExactSynonym "AMD 3100" @default.
- NCIT_C1777 hasExactSynonym "AMD3100" @default.
- NCIT_C1777 hasExactSynonym "JM-3100" @default.
- NCIT_C1777 hasExactSynonym "Mozobil" @default.
- NCIT_C1777 hasExactSynonym "PLERIXAFOR" @default.
- NCIT_C1777 hasExactSynonym "Plerixafor" @default.
- NCIT_C1777 hasExactSynonym "SDZ SID 791" @default.
- NCIT_C1777 hasExactSynonym "plerixafor" @default.
- NCIT_C1777 inSubset NCIT_C116977 @default.
- NCIT_C1777 inSubset NCIT_C116978 @default.
- NCIT_C1777 inSubset NCIT_C176424 @default.
- NCIT_C1777 inSubset NCIT_C186329 @default.
- NCIT_C1777 inSubset NCIT_C186341 @default.
- NCIT_C1777 inSubset NCIT_C63923 @default.
- NCIT_C1777 type Class @default.
- NCIT_C1777 isDefinedBy ncit.owl @default.
- NCIT_C1777 label "Plerixafor" @default.
- NCIT_C1777 subClassOf NCIT_C1777 @default.
- NCIT_C1777 subClassOf NCIT_C1908 @default.
- NCIT_C1777 subClassOf NCIT_C1909 @default.
- NCIT_C1777 subClassOf NCIT_C308 @default.
- NCIT_C1777 subClassOf NCIT_C63817 @default.