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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17780> ?p ?o ?g. }

• NCIT_C17780 IAO_0000115 "Mitogen-activated protein kinase 8 (427 aa, ~48 kDa) is encoded by the human MAPK8 gene. This protein plays a role in serine/threonine phosphorylation, apoptosis and toll-like receptor signaling." @default.
• NCIT_C17780 NCIT_NHC0 "C17780" @default.
• NCIT_C17780 NCIT_P100 "601158" @default.
• NCIT_C17780 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C17780 NCIT_P106 "Enzyme" @default.
• NCIT_C17780 NCIT_P108 "Mitogen-Activated Protein Kinase 8" @default.
• NCIT_C17780 NCIT_P207 "C0380051" @default.
• NCIT_C17780 NCIT_P366 "MAP-Kinase-8" @default.
• NCIT_C17780 NCIT_P93 "P45983" @default.
• NCIT_C17780 NCIT_P98 "Inhibited by dual specificity phosphatases, and phosphothreonine/tyrosine activated by a Ras-dependent dual specificity MAP2K4/MAP2K7 cascade, MAPK8 mediates immediate-early gene expression. MAPK8 binds scaffolding proteins MAPK8IP1/2/3. MAPK8/UV-induced apoptosis appears related to cytochrome c-mediated cell death. MAPK8 activation by TNF-alpha induces apoptosis. MAPK8 appears to be required for T-helper cell differentiation into Th1 cells." @default.
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