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- NCIT_C178318 IAO_0000115 "A small molecule pan inhibitor of human fibroblast growth factor receptors (FGFRs), with potential antiangiogenic and antineoplastic activities. Upon oral administration,gunagratinib inhibits the activities of FGFRs, which may result in the inhibition of both tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. FGFRs, a family of receptor tyrosine kinases upregulated in various tumor cell types, may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival." @default.
- NCIT_C178318 NCIT_A7 NCIT_C17411 @default.
- NCIT_C178318 NCIT_A7 NCIT_C17590 @default.
- NCIT_C178318 NCIT_A7 NCIT_C25859 @default.
- NCIT_C178318 NCIT_A7 NCIT_C26129 @default.
- NCIT_C178318 NCIT_NHC0 "C178318" @default.
- NCIT_C178318 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C178318 NCIT_P107 "Gunagratinib" @default.
- NCIT_C178318 NCIT_P108 "Gunagratinib" @default.
- NCIT_C178318 NCIT_P208 "CL1647816" @default.
- NCIT_C178318 NCIT_P210 "2211082-53-8" @default.
- NCIT_C178318 NCIT_P319 "9D589FD91A" @default.
- NCIT_C178318 NCIT_P322 "CTRP" @default.
- NCIT_C178318 NCIT_P322 "FDA" @default.
- NCIT_C178318 NCIT_P322 "GDC" @default.
- NCIT_C178318 NCIT_P329 "804155" @default.
- NCIT_C178318 NCIT_P330 "804155" @default.
- NCIT_C178318 NCIT_P399 "804155" @default.
- NCIT_C178318 normalizedInformationContent "100" @default.
- NCIT_C178318 referenceCount "1" @default.
- NCIT_C178318 hasExactSynonym "GUNAGRATINIB" @default.
- NCIT_C178318 hasExactSynonym "Gunagratinib" @default.
- NCIT_C178318 hasExactSynonym "ICP 192" @default.
- NCIT_C178318 hasExactSynonym "ICP-192" @default.
- NCIT_C178318 hasExactSynonym "ICP192" @default.
- NCIT_C178318 hasExactSynonym "Pan-FGFR Inhibitor ICP-192" @default.
- NCIT_C178318 inSubset NCIT_C116977 @default.
- NCIT_C178318 inSubset NCIT_C116978 @default.
- NCIT_C178318 inSubset NCIT_C128784 @default.
- NCIT_C178318 inSubset NCIT_C157711 @default.
- NCIT_C178318 inSubset NCIT_C157712 @default.
- NCIT_C178318 inSubset NCIT_C176424 @default.
- NCIT_C178318 inSubset NCIT_C63923 @default.
- NCIT_C178318 type Class @default.
- NCIT_C178318 isDefinedBy ncit.owl @default.
- NCIT_C178318 label "Gunagratinib" @default.
- NCIT_C178318 subClassOf NCIT_C129824 @default.
- NCIT_C178318 subClassOf NCIT_C129825 @default.
- NCIT_C178318 subClassOf NCIT_C1404 @default.
- NCIT_C178318 subClassOf NCIT_C155727 @default.
- NCIT_C178318 subClassOf NCIT_C163758 @default.
- NCIT_C178318 subClassOf NCIT_C164035 @default.
- NCIT_C178318 subClassOf NCIT_C178318 @default.
- NCIT_C178318 subClassOf NCIT_C1908 @default.
- NCIT_C178318 subClassOf NCIT_C1909 @default.
- NCIT_C178318 subClassOf NCIT_C1967 @default.
- NCIT_C178318 subClassOf NCIT_C2189 @default.
- NCIT_C178318 subClassOf NCIT_C274 @default.
- NCIT_C178318 subClassOf NCIT_C471 @default.