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- NCIT_C178338 IAO_0000115 "A prolonged-release multi-kinase inhibitor, with potential anti-angiogenic, anti-fibrotic and antineoplastic activities. Upon intradermal or intratumoral administration, AIV001 targets and binds to several kinases, including vascular endothelial growth factor receptor (VEGFR), and inhibits multiple pathways involved in neovascularization, fibrosis, abnormal cell proliferation and inflammation. This may reduce dermal neovascularization and fibroplasia during wound healing and scarring, reduce inflammation and fibrosis associated with certain skin conditions, and may reduce neovascularization and cell proliferation associated with certain types of cancers." @default.
- NCIT_C178338 NCIT_A7 NCIT_C17293 @default.
- NCIT_C178338 NCIT_NHC0 "C178338" @default.
- NCIT_C178338 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C178338 NCIT_P108 "Multi-kinase Inhbitor AIV001" @default.
- NCIT_C178338 NCIT_P208 "CL1647828" @default.
- NCIT_C178338 NCIT_P322 "GDC" @default.
- NCIT_C178338 NCIT_P329 "804133" @default.
- NCIT_C178338 NCIT_P330 "804133" @default.
- NCIT_C178338 NCIT_P399 "804133" @default.
- NCIT_C178338 normalizedInformationContent "100" @default.
- NCIT_C178338 referenceCount "1" @default.
- NCIT_C178338 hasExactSynonym "AIV 001" @default.
- NCIT_C178338 hasExactSynonym "AIV-001" @default.
- NCIT_C178338 hasExactSynonym "AIV001" @default.
- NCIT_C178338 hasExactSynonym "Multi-kinase Inhbitor AIV001" @default.
- NCIT_C178338 inSubset NCIT_C128784 @default.
- NCIT_C178338 inSubset NCIT_C157711 @default.
- NCIT_C178338 inSubset NCIT_C157712 @default.
- NCIT_C178338 inSubset NCIT_C176424 @default.
- NCIT_C178338 type Class @default.
- NCIT_C178338 isDefinedBy ncit.owl @default.
- NCIT_C178338 label "Multi-kinase Inhbitor AIV001" @default.
- NCIT_C178338 subClassOf NCIT_C129824 @default.
- NCIT_C178338 subClassOf NCIT_C129825 @default.
- NCIT_C178338 subClassOf NCIT_C1404 @default.
- NCIT_C178338 subClassOf NCIT_C178338 @default.
- NCIT_C178338 subClassOf NCIT_C1908 @default.
- NCIT_C178338 subClassOf NCIT_C1909 @default.
- NCIT_C178338 subClassOf NCIT_C2189 @default.
- NCIT_C178338 subClassOf NCIT_C274 @default.
- NCIT_C178338 subClassOf NCIT_C471 @default.