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- NCIT_C178421 IAO_0000115 "A Toll-like receptor (TLR) 7 agonist with potential immunostimulating and antineoplastic activities. Upon administration, TLR7 agonist SHR2150 targets, binds to and activates TLR7. This may trigger, in addition to other possible responses, the activation of dendritic cells (DCs), macrophages and B cells, and activate cluster of differentiation (CD) 8+ T-cells. This may induce anti-tumor immune responses. TLR7 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity." @default.
- NCIT_C178421 NCIT_A7 NCIT_C30108 @default.
- NCIT_C178421 NCIT_NHC0 "C178421" @default.
- NCIT_C178421 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C178421 NCIT_P108 "TLR7 Agonist SHR2150" @default.
- NCIT_C178421 NCIT_P208 "CL1647840" @default.
- NCIT_C178421 NCIT_P322 "GDC" @default.
- NCIT_C178421 NCIT_P329 "804560" @default.
- NCIT_C178421 NCIT_P330 "804560" @default.
- NCIT_C178421 NCIT_P399 "804560" @default.
- NCIT_C178421 normalizedInformationContent "100" @default.
- NCIT_C178421 referenceCount "1" @default.
- NCIT_C178421 hasExactSynonym "SHR 2150" @default.
- NCIT_C178421 hasExactSynonym "SHR-2150" @default.
- NCIT_C178421 hasExactSynonym "SHR2150" @default.
- NCIT_C178421 hasExactSynonym "TLR7 Agonist SHR2150" @default.
- NCIT_C178421 inSubset NCIT_C128784 @default.
- NCIT_C178421 inSubset NCIT_C157711 @default.
- NCIT_C178421 inSubset NCIT_C157712 @default.
- NCIT_C178421 inSubset NCIT_C176424 @default.
- NCIT_C178421 type Class @default.
- NCIT_C178421 isDefinedBy ncit.owl @default.
- NCIT_C178421 label "TLR7 Agonist SHR2150" @default.
- NCIT_C178421 subClassOf NCIT_C177174 @default.
- NCIT_C178421 subClassOf NCIT_C177176 @default.
- NCIT_C178421 subClassOf NCIT_C178421 @default.
- NCIT_C178421 subClassOf NCIT_C1908 @default.
- NCIT_C178421 subClassOf NCIT_C1909 @default.
- NCIT_C178421 subClassOf NCIT_C2139 @default.
- NCIT_C178421 subClassOf NCIT_C308 @default.