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- NCIT_C178447 IAO_0000115 "A preparation of autologous, personalized, immunogenic and tumor neoantigen-specific T-lymphocytes, with potential immunostimulating and antineoplastic activities. Tumor-specific neoantigen targets of autologous CD4+ and/or CD8+ T-cells are identified and T-cells that target immunogenic and stimulatory neoantigens are expanded ex vivo. Upon administration, the autologous neoantigen-specific T-lymphocytes GEN-011 recognize and bind to tumor cells expressing the targeted neoantigens, resulting in a cytotoxic T-lymphocyte (CTL)-mediated immune response against the patient's tumor cells." @default.
- NCIT_C178447 NCIT_NHC0 "C178447" @default.
- NCIT_C178447 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C178447 NCIT_P107 "Autologous Neoantigen-specific T-lymphocytes GEN-011" @default.
- NCIT_C178447 NCIT_P108 "Autologous Neoantigen-specific T-lymphocytes GEN-011" @default.
- NCIT_C178447 NCIT_P208 "CL1648118" @default.
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- NCIT_C178447 hasExactSynonym "Autologous Immunogenic Neoantigen-specific T-cells GEN-011" @default.
- NCIT_C178447 hasExactSynonym "Autologous Neoantigen-specific T-lymphocytes GEN-011" @default.
- NCIT_C178447 hasExactSynonym "Autologous Neoantigen-targeting T-cells GEN-011" @default.
- NCIT_C178447 hasExactSynonym "GEN 011" @default.
- NCIT_C178447 hasExactSynonym "GEN-011" @default.
- NCIT_C178447 hasExactSynonym "GEN011" @default.
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- NCIT_C178447 type Class @default.
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- NCIT_C178447 label "Autologous Neoantigen-specific T-lymphocytes GEN-011" @default.
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