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- NCIT_C179326 IAO_0000115 "A radioconjugate composed of a nanobody directed against human epidermal growth factor receptor 2 (HER2; EGFR2; ERBB2) that is labeled with technetium Tc 99m, with potential use as a tracer for HER2-expressing tumors using single photon emission computed tomography/computed tomography (SPECT/CT). Upon administration of technetium Tc-99m-MIRC208, the anti-HER2 nanobody moiety targets and binds to HER2-expressing tumor cells. This facilitates both the detection of HER2-expressing tumor cells and the assessment of responses to HER2-targeting chemotherapeutic agents using SPECT/CT. HER2, a receptor tyrosine kinase, is overexpressed on the cell surfaces of various tumor cell types; it plays a key role in tumor cell proliferation and tumor vascularization." @default.
- NCIT_C179326 NCIT_A7 NCIT_C17319 @default.
- NCIT_C179326 NCIT_NHC0 "C179326" @default.
- NCIT_C179326 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C179326 NCIT_P108 "Technetium Tc-99m-MIRC208" @default.
- NCIT_C179326 NCIT_P208 "CL1661988" @default.
- NCIT_C179326 NCIT_P399 "804659" @default.
- NCIT_C179326 normalizedInformationContent "100" @default.
- NCIT_C179326 referenceCount "1" @default.
- NCIT_C179326 hasExactSynonym "99mTc-MIRC208" @default.
- NCIT_C179326 hasExactSynonym "Technetium Tc 99m-MIRC208" @default.
- NCIT_C179326 hasExactSynonym "Technetium Tc-99m-MIRC208" @default.
- NCIT_C179326 inSubset NCIT_C176424 @default.
- NCIT_C179326 type Class @default.
- NCIT_C179326 isDefinedBy ncit.owl @default.
- NCIT_C179326 label "Technetium Tc-99m-MIRC208" @default.
- NCIT_C179326 subClassOf NCIT_C1446 @default.
- NCIT_C179326 subClassOf NCIT_C1511 @default.
- NCIT_C179326 subClassOf NCIT_C1512 @default.
- NCIT_C179326 subClassOf NCIT_C179326 @default.
- NCIT_C179326 subClassOf NCIT_C1908 @default.
- NCIT_C179326 subClassOf NCIT_C1909 @default.
- NCIT_C179326 subClassOf NCIT_C2124 @default.
- NCIT_C179326 subClassOf NCIT_C307 @default.
- NCIT_C179326 subClassOf NCIT_C308 @default.