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- NCIT_C179546 IAO_0000115 "A radioimmunoconjugate composed of basiliximab, a chimeric, mouse-human monoclonal antibody directed against the alpha subunit of interleukin-2 receptor (IL-2R alpha, CD25 or Tac antigen), and conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and labeled with the radioisotope indium In 111, with potential use as an imaging agent. Upon administration of indium In 111-DOTA- basiliximab, the basiliximab moiety targets and binds to IL-2R alpha expressed on the surface of activated T-lymphocytes. Upon binding and gamma scintigraphy, IL-2R alpha-expressing T-cells can be visualized and the binding and biodistribution of basiliximab can be assessed." @default.
- NCIT_C179546 NCIT_A7 NCIT_C17073 @default.
- NCIT_C179546 NCIT_NHC0 "C179546" @default.
- NCIT_C179546 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C179546 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C179546 NCIT_P107 "Indium In 111-DOTA-Basiliximab" @default.
- NCIT_C179546 NCIT_P108 "Indium In 111-DOTA-Basiliximab" @default.
- NCIT_C179546 NCIT_P208 "CL1662098" @default.
- NCIT_C179546 NCIT_P322 "CTRP" @default.
- NCIT_C179546 NCIT_P399 "805713" @default.
- NCIT_C179546 normalizedInformationContent "100" @default.
- NCIT_C179546 referenceCount "1" @default.
- NCIT_C179546 hasExactSynonym "111In-DOTA-Basiliximab" @default.
- NCIT_C179546 hasExactSynonym "Indium In 111-DOTA-Basiliximab" @default.
- NCIT_C179546 inSubset NCIT_C116977 @default.
- NCIT_C179546 inSubset NCIT_C116978 @default.
- NCIT_C179546 inSubset NCIT_C176424 @default.
- NCIT_C179546 type Class @default.
- NCIT_C179546 isDefinedBy ncit.owl @default.
- NCIT_C179546 label "Indium In 111-DOTA-Basiliximab" @default.
- NCIT_C179546 subClassOf NCIT_C1446 @default.
- NCIT_C179546 subClassOf NCIT_C1511 @default.
- NCIT_C179546 subClassOf NCIT_C1512 @default.
- NCIT_C179546 subClassOf NCIT_C179546 @default.
- NCIT_C179546 subClassOf NCIT_C1908 @default.
- NCIT_C179546 subClassOf NCIT_C1909 @default.
- NCIT_C179546 subClassOf NCIT_C2124 @default.
- NCIT_C179546 subClassOf NCIT_C307 @default.
- NCIT_C179546 subClassOf NCIT_C308 @default.