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- NCIT_C179630 IAO_0000115 "A preparation of donor-derived T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) directed against the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon intravenous administration, the allogeneic anti-CD7 CAR T cells specifically recognize and bind to CD7-expressing tumor cells, resulting in specific T-cell-mediated tumor cell lysis. CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas." @default.
- NCIT_C179630 NCIT_A7 NCIT_C38935 @default.
- NCIT_C179630 NCIT_NHC0 "C179630" @default.
- NCIT_C179630 NCIT_P106 "Cell" @default.
- NCIT_C179630 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C179630 NCIT_P108 "Allogeneic Anti-CD7 CAR T Cells" @default.
- NCIT_C179630 NCIT_P208 "CL1662143" @default.
- NCIT_C179630 NCIT_P399 "804850" @default.
- NCIT_C179630 normalizedInformationContent "100" @default.
- NCIT_C179630 referenceCount "1" @default.
- NCIT_C179630 hasExactSynonym "Allogeneic Anti-CD7 CAR T Cells" @default.
- NCIT_C179630 hasExactSynonym "Donor Anti-CD7 CAR T Cells" @default.
- NCIT_C179630 hasExactSynonym "Donor-Derived CD7 CAR T Cells" @default.
- NCIT_C179630 inSubset NCIT_C128784 @default.
- NCIT_C179630 inSubset NCIT_C176424 @default.
- NCIT_C179630 type Class @default.
- NCIT_C179630 isDefinedBy ncit.owl @default.
- NCIT_C179630 label "Allogeneic Anti-CD7 CAR T Cells" @default.
- NCIT_C179630 subClassOf NCIT_C129820 @default.
- NCIT_C179630 subClassOf NCIT_C129821 @default.
- NCIT_C179630 subClassOf NCIT_C129826 @default.
- NCIT_C179630 subClassOf NCIT_C137999 @default.
- NCIT_C179630 subClassOf NCIT_C142078 @default.
- NCIT_C179630 subClassOf NCIT_C154231 @default.
- NCIT_C179630 subClassOf NCIT_C179630 @default.
- NCIT_C179630 subClassOf NCIT_C1908 @default.
- NCIT_C179630 subClassOf NCIT_C1909 @default.
- NCIT_C179630 subClassOf NCIT_C1962 @default.
- NCIT_C179630 subClassOf NCIT_C200765 @default.
- NCIT_C179630 subClassOf NCIT_C201177 @default.
- NCIT_C179630 subClassOf NCIT_C274 @default.
- NCIT_C179630 subClassOf NCIT_C28676 @default.
- NCIT_C179630 subClassOf NCIT_C307 @default.
- NCIT_C179630 subClassOf NCIT_C308 @default.