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- NCIT_C179639 IAO_0000115 "A formulation consisting of lipid nanoparticles (LNPs) encapsulating nucleoside-modified messenger RNA (mRNA) encoding the endogenous cytokine interleukin-7 (IL-7), with potential immunostimulating activity. Upon administration, ribocytokine IL-7 BNT152 is taken up by cells and the expressed IL-7 targets and binds to the IL-7 receptor (IL7R). The binding of IL-7 to IL7R activates IL7/IL7R-mediated signaling, which activates B- and T- lymphocytes, may improve immune recovery and activation, and may enhance anti-tumor immune responses." @default.
- NCIT_C179639 NCIT_A7 NCIT_C26278 @default.
- NCIT_C179639 NCIT_NHC0 "C179639" @default.
- NCIT_C179639 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C179639 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C179639 NCIT_P108 "Ribocytokine IL-7 BNT152" @default.
- NCIT_C179639 NCIT_P208 "CL1662150" @default.
- NCIT_C179639 NCIT_P322 "GDC" @default.
- NCIT_C179639 NCIT_P399 "804873" @default.
- NCIT_C179639 NCIT_R124 NCIT_C17828 @default.
- NCIT_C179639 NCIT_R124 NCIT_C18992 @default.
- NCIT_C179639 NCIT_R124 NCIT_C19143 @default.
- NCIT_C179639 NCIT_R124 NCIT_C21124 @default.
- NCIT_C179639 NCIT_R124 NCIT_C40702 @default.
- NCIT_C179639 NCIT_R125 NCIT_C17828 @default.
- NCIT_C179639 NCIT_R125 NCIT_C17937 @default.
- NCIT_C179639 NCIT_R125 NCIT_C18081 @default.
- NCIT_C179639 NCIT_R125 NCIT_C18095 @default.
- NCIT_C179639 NCIT_R125 NCIT_C18839 @default.
- NCIT_C179639 NCIT_R125 NCIT_C20480 @default.
- NCIT_C179639 NCIT_R125 NCIT_C20751 @default.
- NCIT_C179639 NCIT_R125 NCIT_C21124 @default.
- NCIT_C179639 NCIT_R125 NCIT_C26280 @default.
- NCIT_C179639 NCIT_R125 NCIT_C40833 @default.
- NCIT_C179639 NCIT_R125 NCIT_C40912 @default.
- NCIT_C179639 normalizedInformationContent "100" @default.
- NCIT_C179639 referenceCount "1" @default.
- NCIT_C179639 hasExactSynonym "BNT 152" @default.
- NCIT_C179639 hasExactSynonym "BNT-152" @default.
- NCIT_C179639 hasExactSynonym "BNT152" @default.
- NCIT_C179639 hasExactSynonym "Human Interleukin-7 mRNA-encoded BNT152" @default.
- NCIT_C179639 hasExactSynonym "Ribocytokine IL-7 BNT152" @default.
- NCIT_C179639 inSubset NCIT_C128784 @default.
- NCIT_C179639 inSubset NCIT_C157711 @default.
- NCIT_C179639 inSubset NCIT_C157712 @default.
- NCIT_C179639 inSubset NCIT_C176424 @default.
- NCIT_C179639 type Class @default.
- NCIT_C179639 isDefinedBy ncit.owl @default.
- NCIT_C179639 label "Ribocytokine IL-7 BNT152" @default.
- NCIT_C179639 subClassOf NCIT_C1283 @default.
- NCIT_C179639 subClassOf NCIT_C179639 @default.
- NCIT_C179639 subClassOf NCIT_C1908 @default.
- NCIT_C179639 subClassOf NCIT_C1909 @default.
- NCIT_C179639 subClassOf NCIT_C307 @default.
- NCIT_C179639 subClassOf NCIT_C308 @default.
- NCIT_C179639 subClassOf NCIT_C592 @default.
- NCIT_C179639 subClassOf NCIT_C593 @default.