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- NCIT_C179734 IAO_0000115 "A radioimmunoconjugate composed of panitumumab, a human immunoglobulin G2 (IgG2) monoclonal antibody directed against the epidermal growth factor receptor (EGFR; HER1; ErbB1), labeled with the radioisotope indium In 111, with potential use as an imaging agent upon single photon emission computed tomography/computed tomography (SPECT/CT). Upon administration of Indium In 111 panitumumab, the antibody moiety targets and binds to the extracellular domain of EGFR on tumor cells. Upon SPECT/CT imaging, EGFR-expressing tumor cells can be visualized and assessed. EGFR, a receptor tyrosine kinase overexpressed on the cell surfaces of many tumor cell types, plays a key role in tumor cell proliferation." @default.
- NCIT_C179734 NCIT_A7 NCIT_C17068 @default.
- NCIT_C179734 NCIT_NHC0 "C179734" @default.
- NCIT_C179734 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C179734 NCIT_P107 "Indium In 111 Panitumumab" @default.
- NCIT_C179734 NCIT_P108 "Indium In 111 Panitumumab" @default.
- NCIT_C179734 NCIT_P208 "CL1662464" @default.
- NCIT_C179734 NCIT_P322 "CTRP" @default.
- NCIT_C179734 NCIT_P399 "805524" @default.
- NCIT_C179734 normalizedInformationContent "100" @default.
- NCIT_C179734 referenceCount "1" @default.
- NCIT_C179734 hasExactSynonym "111In Panitumumab" @default.
- NCIT_C179734 hasExactSynonym "111In-panitumumab" @default.
- NCIT_C179734 hasExactSynonym "In 111-panitumumab" @default.
- NCIT_C179734 hasExactSynonym "Indium In 111 Panitumumab" @default.
- NCIT_C179734 inSubset NCIT_C116977 @default.
- NCIT_C179734 inSubset NCIT_C116978 @default.
- NCIT_C179734 inSubset NCIT_C176424 @default.
- NCIT_C179734 type Class @default.
- NCIT_C179734 isDefinedBy ncit.owl @default.
- NCIT_C179734 label "Indium In 111 Panitumumab" @default.
- NCIT_C179734 subClassOf NCIT_C1446 @default.
- NCIT_C179734 subClassOf NCIT_C1511 @default.
- NCIT_C179734 subClassOf NCIT_C1512 @default.
- NCIT_C179734 subClassOf NCIT_C179734 @default.
- NCIT_C179734 subClassOf NCIT_C1908 @default.
- NCIT_C179734 subClassOf NCIT_C1909 @default.
- NCIT_C179734 subClassOf NCIT_C2124 @default.
- NCIT_C179734 subClassOf NCIT_C307 @default.
- NCIT_C179734 subClassOf NCIT_C308 @default.