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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1798> ?p ?o ?g. }

• NCIT_C1798 IAO_0000115 "A multifunctional antiangiogenic agent derived from shark cartilage with potential antineoplastic activity. Shark cartilage extract AE-941 competitively inhibits the binding of pro-angiogenic vascular endothelial growth factor (VEGF) to its cellular receptor, thereby inhibiting endothelial cell proliferation. This agent also inhibits matrix metalloproteinases (MMPs), stimulates tissue plasminogen activator (tPA), and activates caspase-mediated apoptotic pathways in endothelial cells." @default.
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• NCIT_C1798 NCIT_P106 "Organic Chemical" @default.
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• NCIT_C1798 NCIT_P107 "Shark Cartilage Extract AE-941" @default.
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• NCIT_C1798 NCIT_P325 "A substance made from shark cartilage that is being studied for its ability to prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent." @default.
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• NCIT_C1798 hasExactSynonym "AE-941" @default.
• NCIT_C1798 hasExactSynonym "Neovastat" @default.
• NCIT_C1798 hasExactSynonym "Shark Cartilage Extract AE-941" @default.
• NCIT_C1798 hasExactSynonym "[AElig]-941" @default.
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• NCIT_C1798 label "Shark Cartilage Extract AE-941" @default.
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