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- NCIT_C17988 IAO_0000115 "G1/S-specific cyclin-D1 (295 aa, ~34 kDa) is encoded by the human CCND1 gene. This protein is involved in the regulation of the G1/S transition of the cell cycle." @default.
- NCIT_C17988 NCIT_A32 NCIT_C268 @default.
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- NCIT_C17988 NCIT_P100 "168461" @default.
- NCIT_C17988 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17988 NCIT_P107 "G1/S-Specific Cyclin-D1" @default.
- NCIT_C17988 NCIT_P108 "G1/S-Specific Cyclin-D1" @default.
- NCIT_C17988 NCIT_P207 "C1741716" @default.
- NCIT_C17988 NCIT_P322 "CTRP" @default.
- NCIT_C17988 NCIT_P322 "GDC" @default.
- NCIT_C17988 NCIT_P366 "Cyclin-D1" @default.
- NCIT_C17988 NCIT_P375 "CCND1" @default.
- NCIT_C17988 NCIT_P93 "P24385" @default.
- NCIT_C17988 NCIT_P98 "Essential for control of the G1/S transition, cyclin D1 interacts with CDK4 and CDK6 to form a serine/threonine kinase holoenzyme and imparts substrate specificity to the complex. RB regulates cyclin D1 gene expression. Cyclin D1 expression may identify Barrett's esophagus patients at high risk for esophageal carcinoma; risk of progression to adenocarcinoma exhibits an odds ratio of 6.85. The BCL1 and PRAD1 oncogenes involve cyclin D1 gene translocations. (J Natl Cancer Inst 2000. 92:1282 & 1316, SWISS-PROT, OMIM)" @default.
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- NCIT_C17988 hasExactSynonym "BCL-1 Oncogene" @default.
- NCIT_C17988 hasExactSynonym "BCL1" @default.
- NCIT_C17988 hasExactSynonym "CCND1" @default.
- NCIT_C17988 hasExactSynonym "CCND1a" @default.
- NCIT_C17988 hasExactSynonym "Cyclin D" @default.
- NCIT_C17988 hasExactSynonym "Cyclin D1" @default.
- NCIT_C17988 hasExactSynonym "Cyclin D1a" @default.
- NCIT_C17988 hasExactSynonym "Cyclin-D1" @default.
- NCIT_C17988 hasExactSynonym "Cyclin-D1a" @default.
- NCIT_C17988 hasExactSynonym "D11S287E" @default.
- NCIT_C17988 hasExactSynonym "G1/S-Specific Cyclin D1" @default.
- NCIT_C17988 hasExactSynonym "G1/S-Specific Cyclin D1a" @default.
- NCIT_C17988 hasExactSynonym "G1/S-Specific Cyclin-D1" @default.
- NCIT_C17988 hasExactSynonym "G1/S-Specific Cyclin-D1a" @default.
- NCIT_C17988 hasExactSynonym "PRAD1 Oncogene" @default.
- NCIT_C17988 hasExactSynonym "PRAD1" @default.
- NCIT_C17988 hasExactSynonym "U21B31" @default.
- NCIT_C17988 inSubset NCIT_C116977 @default.
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- NCIT_C17988 type Class @default.
- NCIT_C17988 isDefinedBy ncit.owl @default.
- NCIT_C17988 label "G1/S-Specific Cyclin-D1" @default.
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