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- NCIT_C1804 IAO_0000115 "A quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks the folate-binding site of thymidylate synthase, thereby inhibiting tetrahydrofolate activity and DNA replication and repair and resulting in cytotoxicity. (NCI04)" @default.
- NCIT_C1804 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1804 NCIT_A7 NCIT_C17199 @default.
- NCIT_C1804 NCIT_NHC0 "C1804" @default.
- NCIT_C1804 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1804 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1804 NCIT_P107 "Raltitrexed" @default.
- NCIT_C1804 NCIT_P108 "Raltitrexed" @default.
- NCIT_C1804 NCIT_P175 "639186" @default.
- NCIT_C1804 NCIT_P207 "C0677667" @default.
- NCIT_C1804 NCIT_P210 "112887-68-0" @default.
- NCIT_C1804 NCIT_P319 "FCB9EGG971" @default.
- NCIT_C1804 NCIT_P322 "CTRP" @default.
- NCIT_C1804 NCIT_P322 "FDA" @default.
- NCIT_C1804 NCIT_P322 "GDC" @default.
- NCIT_C1804 NCIT_P325 "An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA. It belongs to the family of drugs called thymidylate synthase inhibitors." @default.
- NCIT_C1804 NCIT_P329 "42625" @default.
- NCIT_C1804 NCIT_P330 "42625" @default.
- NCIT_C1804 NCIT_P350 "C21H22N4O6S" @default.
- NCIT_C1804 NCIT_P366 "Raltitrexed" @default.
- NCIT_C1804 NCIT_P375 "Raltitrexed" @default.
- NCIT_C1804 NCIT_P399 "42625" @default.
- NCIT_C1804 NCIT_R124 NCIT_C17710 @default.
- NCIT_C1804 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1804 NCIT_R124 NCIT_C28498 @default.
- NCIT_C1804 NCIT_R124 NCIT_C40576 @default.
- NCIT_C1804 NCIT_R124 NCIT_C40577 @default.
- NCIT_C1804 NCIT_R125 NCIT_C17710 @default.
- NCIT_C1804 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1804 NCIT_R125 NCIT_C18125 @default.
- NCIT_C1804 NCIT_R125 NCIT_C21080 @default.
- NCIT_C1804 NCIT_R125 NCIT_C28498 @default.
- NCIT_C1804 NCIT_R125 NCIT_C40664 @default.
- NCIT_C1804 NCIT_R125 NCIT_C41543 @default.
- NCIT_C1804 NCIT_R146 NCIT_C16554 @default.
- NCIT_C1804 NCIT_R146 NCIT_C16849 @default.
- NCIT_C1804 NCIT_R146 NCIT_C17021 @default.
- NCIT_C1804 NCIT_R146 NCIT_C17199 @default.
- NCIT_C1804 NCIT_R146 NCIT_C17210 @default.
- NCIT_C1804 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1804 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1804 normalizedInformationContent "88.143637090998837" @default.
- NCIT_C1804 referenceCount "6" @default.
- NCIT_C1804 hasExactSynonym "D1694" @default.
- NCIT_C1804 hasExactSynonym "ICI D1694" @default.
- NCIT_C1804 hasExactSynonym "N-(5-[N-(3,4-Dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl)-L-glutamic Acid" @default.
- NCIT_C1804 hasExactSynonym "N-[[5-[[(1,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic Acid" @default.
- NCIT_C1804 hasExactSynonym "RALTITREXED" @default.
- NCIT_C1804 hasExactSynonym "Raltitrexed" @default.
- NCIT_C1804 hasExactSynonym "ZD 1694" @default.
- NCIT_C1804 hasExactSynonym "ZD-1694" @default.
- NCIT_C1804 hasExactSynonym "ZD1694" @default.
- NCIT_C1804 hasExactSynonym "raltitrexed" @default.
- NCIT_C1804 inSubset NCIT_C116977 @default.
- NCIT_C1804 inSubset NCIT_C116978 @default.
- NCIT_C1804 inSubset NCIT_C128784 @default.
- NCIT_C1804 inSubset NCIT_C157711 @default.
- NCIT_C1804 inSubset NCIT_C157712 @default.
- NCIT_C1804 inSubset NCIT_C176424 @default.
- NCIT_C1804 inSubset NCIT_C177537 @default.
- NCIT_C1804 inSubset NCIT_C63923 @default.
- NCIT_C1804 type Class @default.
- NCIT_C1804 isDefinedBy ncit.owl @default.
- NCIT_C1804 label "Raltitrexed" @default.
- NCIT_C1804 subClassOf NCIT_C1804 @default.
- NCIT_C1804 subClassOf NCIT_C186664 @default.
- NCIT_C1804 subClassOf NCIT_C1908 @default.
- NCIT_C1804 subClassOf NCIT_C1909 @default.
- NCIT_C1804 subClassOf NCIT_C2021 @default.
- NCIT_C1804 subClassOf NCIT_C272 @default.
- NCIT_C1804 subClassOf NCIT_C274 @default.
- NCIT_C1804 subClassOf NCIT_C471 @default.
- NCIT_C1804 subClassOf NCIT_C511 @default.
- NCIT_C1804 equivalentClass B9059f33ea5fee5c2b89f5e1ed5a021fb @default.
- NCIT_C1804 equivalentClass Be996aecadc43d5632a14fca8385c8819 @default.