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- NCIT_C180526 IAO_0000115 "The besylate salt form of clifutinib, an orally bioavailable, selective, small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential antineoplastic activity. Upon oral administration, clifutinib targets, binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias." @default.
- NCIT_C180526 NCIT_A6 NCIT_C180527 @default.
- NCIT_C180526 NCIT_A7 NCIT_C26202 @default.
- NCIT_C180526 NCIT_NHC0 "C180526" @default.
- NCIT_C180526 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180526 NCIT_P108 "Clifutinib Besylate" @default.
- NCIT_C180526 NCIT_P208 "CL1663045" @default.
- NCIT_C180526 NCIT_P322 "GDC" @default.
- NCIT_C180526 NCIT_P399 "805150" @default.
- NCIT_C180526 normalizedInformationContent "100" @default.
- NCIT_C180526 referenceCount "1" @default.
- NCIT_C180526 hasExactSynonym "Clifutinib Besylate" @default.
- NCIT_C180526 hasExactSynonym "HEC 73543" @default.
- NCIT_C180526 hasExactSynonym "HEC-73543" @default.
- NCIT_C180526 hasExactSynonym "HEC73543" @default.
- NCIT_C180526 inSubset NCIT_C128784 @default.
- NCIT_C180526 inSubset NCIT_C157711 @default.
- NCIT_C180526 inSubset NCIT_C157712 @default.
- NCIT_C180526 inSubset NCIT_C176424 @default.
- NCIT_C180526 type Class @default.
- NCIT_C180526 isDefinedBy ncit.owl @default.
- NCIT_C180526 label "Clifutinib Besylate" @default.
- NCIT_C180526 subClassOf NCIT_C124800 @default.
- NCIT_C180526 subClassOf NCIT_C1404 @default.
- NCIT_C180526 subClassOf NCIT_C163758 @default.
- NCIT_C180526 subClassOf NCIT_C163790 @default.
- NCIT_C180526 subClassOf NCIT_C180526 @default.
- NCIT_C180526 subClassOf NCIT_C1908 @default.
- NCIT_C180526 subClassOf NCIT_C1909 @default.
- NCIT_C180526 subClassOf NCIT_C1967 @default.
- NCIT_C180526 subClassOf NCIT_C274 @default.
- NCIT_C180526 subClassOf NCIT_C471 @default.