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- NCIT_C180588 IAO_0000115 "A recombinant protein-based inhibitor of numerous types of kallikrein-related peptidases (KLKs), with potential antineoplastic activity. Upon administration, KLK inhibitor MDPK67b targets and inhibits various KLKs, including KLK2, KLK4, KLK5 and KLK14. This inhibits KLK-mediated signaling and inhibits the proliferation of tumor cells in which these KLKs are overexpressed. Deregulation of KLKs is associated with some types of cancers." @default.
- NCIT_C180588 NCIT_A7 NCIT_C16767 @default.
- NCIT_C180588 NCIT_A7 NCIT_C18163 @default.
- NCIT_C180588 NCIT_NHC0 "C180588" @default.
- NCIT_C180588 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180588 NCIT_P108 "Kallikrein Inhibitor MDPK67b" @default.
- NCIT_C180588 NCIT_P208 "CL1662948" @default.
- NCIT_C180588 NCIT_P322 "GDC" @default.
- NCIT_C180588 NCIT_P399 "805502" @default.
- NCIT_C180588 normalizedInformationContent "100" @default.
- NCIT_C180588 referenceCount "1" @default.
- NCIT_C180588 hasExactSynonym "KLK Inhibitor MDPK67b" @default.
- NCIT_C180588 hasExactSynonym "Kallikrein Inhibitor MDPK67b" @default.
- NCIT_C180588 hasExactSynonym "MDPK 67b" @default.
- NCIT_C180588 hasExactSynonym "MDPK-67b" @default.
- NCIT_C180588 hasExactSynonym "MDPK67b" @default.
- NCIT_C180588 inSubset NCIT_C128784 @default.
- NCIT_C180588 inSubset NCIT_C157711 @default.
- NCIT_C180588 inSubset NCIT_C157712 @default.
- NCIT_C180588 inSubset NCIT_C176424 @default.
- NCIT_C180588 type Class @default.
- NCIT_C180588 isDefinedBy ncit.owl @default.
- NCIT_C180588 label "Kallikrein Inhibitor MDPK67b" @default.
- NCIT_C180588 subClassOf NCIT_C1404 @default.
- NCIT_C180588 subClassOf NCIT_C180588 @default.
- NCIT_C180588 subClassOf NCIT_C1908 @default.
- NCIT_C180588 subClassOf NCIT_C1909 @default.
- NCIT_C180588 subClassOf NCIT_C471 @default.