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- NCIT_C180598 IAO_0000115 "A preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-HER2 CAR-T cells target and bind to HER2-expressing tumor cells, thereby inducing selective toxicity in HER2-expressing tumor cells. HER2 is overexpressed in a variety of cancer cell types and is associated with increased tumor cell proliferation." @default.
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- NCIT_C180598 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180598 NCIT_P107 "Autologous Anti-HER2 CAR-T Cells" @default.
- NCIT_C180598 NCIT_P108 "Autologous Anti-HER2 CAR-T Cells" @default.
- NCIT_C180598 NCIT_P208 "CL1662934" @default.
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- NCIT_C180598 hasExactSynonym "Autologous Anti-HER2 CAR T-cells" @default.
- NCIT_C180598 hasExactSynonym "Autologous Anti-HER2 CAR-T Cells" @default.
- NCIT_C180598 hasExactSynonym "Autologous HER2-specific CAR T Cells" @default.
- NCIT_C180598 inSubset NCIT_C116977 @default.
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- NCIT_C180598 type Class @default.
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- NCIT_C180598 label "Autologous Anti-HER2 CAR-T Cells" @default.
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