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- NCIT_C180680 IAO_0000115 "An orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic activity. Upon oral administration, AR antagonist TQB3720 specifically targets and binds to the AR, thereby inhibiting both AR activation and the AR-mediated signaling pathway. This may inhibit cell growth in AR-overexpressing tumor cells. AR is overexpressed in prostate cancers and is involved in the proliferation, survival and chemoresistance of tumor cells." @default.
- NCIT_C180680 NCIT_A7 NCIT_C17063 @default.
- NCIT_C180680 NCIT_NHC0 "C180680" @default.
- NCIT_C180680 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180680 NCIT_P108 "Androgen Receptor Antagonist TQB3720" @default.
- NCIT_C180680 NCIT_P208 "CL1663339" @default.
- NCIT_C180680 NCIT_P322 "GDC" @default.
- NCIT_C180680 NCIT_P399 "805545" @default.
- NCIT_C180680 normalizedInformationContent "100" @default.
- NCIT_C180680 referenceCount "1" @default.
- NCIT_C180680 hasExactSynonym "AR Antagonist TQB3720" @default.
- NCIT_C180680 hasExactSynonym "Androgen Receptor Antagonist TQB3720" @default.
- NCIT_C180680 hasExactSynonym "TQB 3720" @default.
- NCIT_C180680 hasExactSynonym "TQB-3720" @default.
- NCIT_C180680 hasExactSynonym "TQB3720" @default.
- NCIT_C180680 inSubset NCIT_C128784 @default.
- NCIT_C180680 inSubset NCIT_C157711 @default.
- NCIT_C180680 inSubset NCIT_C157712 @default.
- NCIT_C180680 inSubset NCIT_C176424 @default.
- NCIT_C180680 type Class @default.
- NCIT_C180680 isDefinedBy ncit.owl @default.
- NCIT_C180680 label "Androgen Receptor Antagonist TQB3720" @default.
- NCIT_C180680 subClassOf NCIT_C146993 @default.
- NCIT_C180680 subClassOf NCIT_C147908 @default.
- NCIT_C180680 subClassOf NCIT_C163758 @default.
- NCIT_C180680 subClassOf NCIT_C180680 @default.
- NCIT_C180680 subClassOf NCIT_C1908 @default.
- NCIT_C180680 subClassOf NCIT_C1909 @default.
- NCIT_C180680 subClassOf NCIT_C242 @default.
- NCIT_C180680 subClassOf NCIT_C274 @default.
- NCIT_C180680 subClassOf NCIT_C547 @default.