Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C180831> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- NCIT_C180831 IAO_0000115 "A humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137 (4-1BB; tumor necrosis factor receptor superfamily member 9; TNFRSF9), with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD137 agonistic monoclonal antibody EU101 targets and binds to CD137 expressed on a variety of leukocyte subsets including activated T-lymphocytes and natural killer (NK) cells. This enhances CD137-mediated signaling, induces cytotoxic T-lymphocyte (CTL) proliferation, cytokine production and promotes a CTL-mediated anti-tumor immune response as well as induces NK-mediated tumor cell killing and suppresses the immunosuppressive activity of regulatory T-cells (Tregs). CD137, a surface glycoprotein of the tumor necrosis factor receptor superfamily, is an inducible costimulatory receptor that plays a key role in T-cell proliferation, survival and cytolytic activity." @default.
- NCIT_C180831 NCIT_A7 NCIT_C105113 @default.
- NCIT_C180831 NCIT_NHC0 "C180831" @default.
- NCIT_C180831 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180831 NCIT_P107 "Anti-CD137 Agonistic Monoclonal Antibody EU101" @default.
- NCIT_C180831 NCIT_P108 "Anti-CD137 Agonistic Monoclonal Antibody EU101" @default.
- NCIT_C180831 NCIT_P208 "CL1663466" @default.
- NCIT_C180831 NCIT_P322 "CTRP" @default.
- NCIT_C180831 NCIT_P322 "GDC" @default.
- NCIT_C180831 NCIT_P399 "805636" @default.
- NCIT_C180831 NCIT_R124 NCIT_C17710 @default.
- NCIT_C180831 NCIT_R124 NCIT_C17828 @default.
- NCIT_C180831 NCIT_R124 NCIT_C18219 @default.
- NCIT_C180831 NCIT_R124 NCIT_C19986 @default.
- NCIT_C180831 NCIT_R124 NCIT_C40474 @default.
- NCIT_C180831 NCIT_R125 NCIT_C16298 @default.
- NCIT_C180831 NCIT_R125 NCIT_C17709 @default.
- NCIT_C180831 NCIT_R125 NCIT_C17828 @default.
- NCIT_C180831 NCIT_R125 NCIT_C17930 @default.
- NCIT_C180831 NCIT_R125 NCIT_C17937 @default.
- NCIT_C180831 NCIT_R125 NCIT_C18839 @default.
- NCIT_C180831 NCIT_R125 NCIT_C21124 @default.
- NCIT_C180831 NCIT_R72 NCIT_C104083 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12219 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12474 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12476 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12508 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12535 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12542 @default.
- NCIT_C180831 NCIT_R72 NCIT_C12543 @default.
- NCIT_C180831 NCIT_R72 NCIT_C21599 @default.
- NCIT_C180831 NCIT_R72 NCIT_C32725 @default.
- NCIT_C180831 NCIT_R72 NCIT_C33061 @default.
- NCIT_C180831 NCIT_R72 NCIT_C38434 @default.
- NCIT_C180831 NCIT_R72 NCIT_C38439 @default.
- NCIT_C180831 NCIT_R72 NCIT_C39567 @default.
- NCIT_C180831 NCIT_R72 NCIT_C39568 @default.
- NCIT_C180831 normalizedInformationContent "100" @default.
- NCIT_C180831 referenceCount "1" @default.
- NCIT_C180831 hasExactSynonym "Agonistic Anti-4-1BB Monoclonal Antibody EU101" @default.
- NCIT_C180831 hasExactSynonym "Anti-CD137 Agonist Monoclonal Antibody EU101" @default.
- NCIT_C180831 hasExactSynonym "Anti-CD137 Agonistic Monoclonal Antibody EU101" @default.
- NCIT_C180831 hasExactSynonym "Anti-CD137 Monoclonal Antibody EU101" @default.
- NCIT_C180831 hasExactSynonym "EU 101" @default.
- NCIT_C180831 hasExactSynonym "EU-101" @default.
- NCIT_C180831 hasExactSynonym "EU101" @default.
- NCIT_C180831 inSubset NCIT_C116977 @default.
- NCIT_C180831 inSubset NCIT_C116978 @default.
- NCIT_C180831 inSubset NCIT_C128784 @default.
- NCIT_C180831 inSubset NCIT_C157711 @default.
- NCIT_C180831 inSubset NCIT_C157712 @default.
- NCIT_C180831 inSubset NCIT_C176424 @default.
- NCIT_C180831 type Class @default.
- NCIT_C180831 isDefinedBy ncit.owl @default.
- NCIT_C180831 label "Anti-CD137 Agonistic Monoclonal Antibody EU101" @default.
- NCIT_C180831 subClassOf B06dde46ed20f59a9682fbec4a2162557 @default.
- NCIT_C180831 subClassOf B1907c9583a9c78ba1e221326824e5377 @default.
- NCIT_C180831 subClassOf B2f471e0150ac981d4740a0364edfec40 @default.
- NCIT_C180831 subClassOf B5b40dbdf068ebbe634a0752876af1a81 @default.
- NCIT_C180831 subClassOf B957112a972eaec8d467845d46bd1a2d4 @default.
- NCIT_C180831 subClassOf B9e1910fe2c85f747b62cec9b51d48198 @default.
- NCIT_C180831 subClassOf Bcbd20d6c5762da05d3a7d5f26463109a @default.
- NCIT_C180831 subClassOf Bd7cc75d57be55f5558660e908d1fe4ab @default.
- NCIT_C180831 subClassOf NCIT_C129820 @default.
- NCIT_C180831 subClassOf NCIT_C155745 @default.
- NCIT_C180831 subClassOf NCIT_C180831 @default.
- NCIT_C180831 subClassOf NCIT_C1908 @default.
- NCIT_C180831 subClassOf NCIT_C1909 @default.
- NCIT_C180831 subClassOf NCIT_C192997 @default.
- NCIT_C180831 subClassOf NCIT_C20401 @default.
- NCIT_C180831 subClassOf NCIT_C274 @default.
- NCIT_C180831 subClassOf NCIT_C307 @default.
- NCIT_C180831 subClassOf NCIT_C308 @default.