Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C180835> ?p ?o ?g. }
Showing items 1 to 41 of
41
with 100 items per page.
- NCIT_C180835 IAO_0000115 "An orally available inhibitor of class I, II, and III B-Raf (BRAF) protein kinases, with potential antineoplastic activity. Upon administration, exarafenib binds to and inhibits Class I, Class II, or Class III B-Raf mutations. This prevents B-Raf-mediated signal transduction pathways, which may lead to an inhibition of tumor growth in B-Raf mutant cells. B-Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated and mutated in human cancers, and plays a key role in tumor cell proliferation and survival." @default.
- NCIT_C180835 NCIT_A7 NCIT_C17476 @default.
- NCIT_C180835 NCIT_A7 NCIT_C17484 @default.
- NCIT_C180835 NCIT_NHC0 "C180835" @default.
- NCIT_C180835 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C180835 NCIT_P108 "Exarafenib" @default.
- NCIT_C180835 NCIT_P208 "CL1663470" @default.
- NCIT_C180835 NCIT_P210 "2639957-39-2" @default.
- NCIT_C180835 NCIT_P319 "2VPX8HL8AB" @default.
- NCIT_C180835 NCIT_P322 "FDA" @default.
- NCIT_C180835 NCIT_P322 "GDC" @default.
- NCIT_C180835 NCIT_P399 "805643" @default.
- NCIT_C180835 normalizedInformationContent "100" @default.
- NCIT_C180835 referenceCount "1" @default.
- NCIT_C180835 hasExactSynonym "B-Raf Inhibitor KIN-2787" @default.
- NCIT_C180835 hasExactSynonym "EXARAFENIB" @default.
- NCIT_C180835 hasExactSynonym "Exarafenib" @default.
- NCIT_C180835 hasExactSynonym "KIN 2787" @default.
- NCIT_C180835 hasExactSynonym "KIN-2787" @default.
- NCIT_C180835 hasExactSynonym "KIN2787" @default.
- NCIT_C180835 hasExactSynonym "pan-Raf Inhibitor KIN-2787" @default.
- NCIT_C180835 inSubset NCIT_C128784 @default.
- NCIT_C180835 inSubset NCIT_C157711 @default.
- NCIT_C180835 inSubset NCIT_C157712 @default.
- NCIT_C180835 inSubset NCIT_C176424 @default.
- NCIT_C180835 inSubset NCIT_C63923 @default.
- NCIT_C180835 type Class @default.
- NCIT_C180835 isDefinedBy ncit.owl @default.
- NCIT_C180835 label "Exarafenib" @default.
- NCIT_C180835 subClassOf NCIT_C129824 @default.
- NCIT_C180835 subClassOf NCIT_C129825 @default.
- NCIT_C180835 subClassOf NCIT_C1404 @default.
- NCIT_C180835 subClassOf NCIT_C163758 @default.
- NCIT_C180835 subClassOf NCIT_C180835 @default.
- NCIT_C180835 subClassOf NCIT_C1908 @default.
- NCIT_C180835 subClassOf NCIT_C1909 @default.
- NCIT_C180835 subClassOf NCIT_C2189 @default.
- NCIT_C180835 subClassOf NCIT_C2336 @default.
- NCIT_C180835 subClassOf NCIT_C274 @default.
- NCIT_C180835 subClassOf NCIT_C471 @default.
- NCIT_C180835 subClassOf NCIT_C61074 @default.