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- NCIT_C181024 IAO_0000115 "A preparation of T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) directed against the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CD7 CAR T cells SenL-T7 specifically recognize and bind to CD7-expressing tumor cells, resulting in specific T-cell-mediated tumor cell lysis. CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas." @default.
- NCIT_C181024 NCIT_A7 NCIT_C38935 @default.
- NCIT_C181024 NCIT_NHC0 "C181024" @default.
- NCIT_C181024 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C181024 NCIT_P108 "Anti-CD7 CAR T Cells SenL-T7" @default.
- NCIT_C181024 NCIT_P208 "CL1663612" @default.
- NCIT_C181024 NCIT_P322 "GDC" @default.
- NCIT_C181024 NCIT_P399 "805819" @default.
- NCIT_C181024 normalizedInformationContent "100" @default.
- NCIT_C181024 referenceCount "1" @default.
- NCIT_C181024 hasExactSynonym "Anti-CD7 CAR T Cells SenL-T7" @default.
- NCIT_C181024 hasExactSynonym "Anti-CD7 CAR T-cells SenL-T7" @default.
- NCIT_C181024 hasExactSynonym "Anti-CD7 CAR-T Cells SenL-T7" @default.
- NCIT_C181024 hasExactSynonym "SenL T7" @default.
- NCIT_C181024 hasExactSynonym "SenL-T7" @default.
- NCIT_C181024 hasExactSynonym "SenLT7" @default.
- NCIT_C181024 inSubset NCIT_C128784 @default.
- NCIT_C181024 inSubset NCIT_C157711 @default.
- NCIT_C181024 inSubset NCIT_C157712 @default.
- NCIT_C181024 inSubset NCIT_C176424 @default.
- NCIT_C181024 type Class @default.
- NCIT_C181024 isDefinedBy ncit.owl @default.
- NCIT_C181024 label "Anti-CD7 CAR T Cells SenL-T7" @default.
- NCIT_C181024 subClassOf NCIT_C129820 @default.
- NCIT_C181024 subClassOf NCIT_C129821 @default.
- NCIT_C181024 subClassOf NCIT_C129826 @default.
- NCIT_C181024 subClassOf NCIT_C137999 @default.
- NCIT_C181024 subClassOf NCIT_C142078 @default.
- NCIT_C181024 subClassOf NCIT_C154231 @default.
- NCIT_C181024 subClassOf NCIT_C181024 @default.
- NCIT_C181024 subClassOf NCIT_C1908 @default.
- NCIT_C181024 subClassOf NCIT_C1909 @default.
- NCIT_C181024 subClassOf NCIT_C1962 @default.
- NCIT_C181024 subClassOf NCIT_C201177 @default.
- NCIT_C181024 subClassOf NCIT_C274 @default.
- NCIT_C181024 subClassOf NCIT_C307 @default.
- NCIT_C181024 subClassOf NCIT_C308 @default.