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- NCIT_C1811 IAO_0000115 "A synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier. (NCI04)" @default.
- NCIT_C1811 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1811 NCIT_NHC0 "C1811" @default.
- NCIT_C1811 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1811 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1811 NCIT_P108 "Prinomastat" @default.
- NCIT_C1811 NCIT_P207 "C0919273" @default.
- NCIT_C1811 NCIT_P210 "192329-42-3" @default.
- NCIT_C1811 NCIT_P319 "10T6626FRK" @default.
- NCIT_C1811 NCIT_P322 "FDA" @default.
- NCIT_C1811 NCIT_P322 "GDC" @default.
- NCIT_C1811 NCIT_P325 "An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Prinomastat is a matrix metalloproteinase inhibitor." @default.
- NCIT_C1811 NCIT_P329 "43058" @default.
- NCIT_C1811 NCIT_P330 "43058" @default.
- NCIT_C1811 NCIT_P350 "C18H21N3O5S2" @default.
- NCIT_C1811 NCIT_P366 "Prinomastat" @default.
- NCIT_C1811 NCIT_P375 "Prinomastat" @default.
- NCIT_C1811 NCIT_P399 "43058" @default.
- NCIT_C1811 normalizedInformationContent "86.239998175184226" @default.
- NCIT_C1811 referenceCount "8" @default.
- NCIT_C1811 hasExactSynonym "(3S)-N-Hydroxy-2,2-dimethyl-4-{{4-(4-piridinyloxy)phenyl}sulfonyl}-3-thiomorpholinecarboxamide" @default.
- NCIT_C1811 hasExactSynonym "AG3340" @default.
- NCIT_C1811 hasExactSynonym "PRINOMASTAT" @default.
- NCIT_C1811 hasExactSynonym "Prinomastat" @default.
- NCIT_C1811 hasExactSynonym "prinomastat" @default.
- NCIT_C1811 inSubset NCIT_C128784 @default.
- NCIT_C1811 inSubset NCIT_C157711 @default.
- NCIT_C1811 inSubset NCIT_C157712 @default.
- NCIT_C1811 inSubset NCIT_C176424 @default.
- NCIT_C1811 inSubset NCIT_C177537 @default.
- NCIT_C1811 inSubset NCIT_C63923 @default.
- NCIT_C1811 type Class @default.
- NCIT_C1811 isDefinedBy ncit.owl @default.
- NCIT_C1811 label "Prinomastat" @default.
- NCIT_C1811 subClassOf NCIT_C1742 @default.
- NCIT_C1811 subClassOf NCIT_C1811 @default.
- NCIT_C1811 subClassOf NCIT_C1908 @default.
- NCIT_C1811 subClassOf NCIT_C1909 @default.
- NCIT_C1811 subClassOf NCIT_C1970 @default.
- NCIT_C1811 subClassOf NCIT_C274 @default.
- NCIT_C1811 subClassOf NCIT_C471 @default.
- NCIT_C1811 subClassOf NCIT_C783 @default.