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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C18115> ?p ?o ?g. }

• NCIT_C18115 IAO_0000115 "Apoptosis regulator Bcl-2 (239 aa, ~26 kDa) is encoded by the human BCL2 gene. This protein plays a role in cellular survival." @default.
• NCIT_C18115 NCIT_NHC0 "C18115" @default.
• NCIT_C18115 NCIT_P100 "151430" @default.
• NCIT_C18115 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C18115 NCIT_P107 "Apoptosis Regulator Bcl-2" @default.
• NCIT_C18115 NCIT_P108 "Apoptosis Regulator Bcl-2" @default.
• NCIT_C18115 NCIT_P207 "C4042483" @default.
• NCIT_C18115 NCIT_P322 "CTRP" @default.
• NCIT_C18115 NCIT_P325 "A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome 18, and transfer of the BCL2 gene to a different chromosome is seen in many B-cell leukemias and lymphomas. This causes the BCL2 protein to be made in larger amounts, which may keep cancer cells from dying." @default.
• NCIT_C18115 NCIT_P366 "B-Cell_CLL_Lymphoma-2" @default.
• NCIT_C18115 NCIT_P93 "P10415" @default.
• NCIT_C18115 NCIT_P98 "A mitochondrial membrane protein, BCL-2 protein is responsible for blocking apoptosis in normal cells. Growth factor-stimulated phosphorylation by PKC promotes anti-apoptotic activity of BCL-2 during G2/M. BCL-2 regulates cell death by controlling mitochondrial membrane permeability. Cleavage by caspases during apoptosis yields a pro-apoptotic BCL-2 product that causes release of cytochrome C into the cytosol, promoting further caspase activity. Over expression from translocation t(14;18) of BCL-2 with the immunoglobulin gene region is involved in B-cell lymphomas. (from OMIM 151430 and NCI)" @default.
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• NCIT_C18115 normalizedInformationContent "92.730304365937428" @default.
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• NCIT_C18115 hasExactSynonym "Apoptosis Regulator Bcl-2" @default.
• NCIT_C18115 hasExactSynonym "B-Cell CLL/lymphoma 2" @default.
• NCIT_C18115 hasExactSynonym "B-cell leukemia/lymphoma 2 protein" @default.
• NCIT_C18115 hasExactSynonym "BCL-2 Protein" @default.
• NCIT_C18115 hasExactSynonym "BCL2" @default.
• NCIT_C18115 inSubset NCIT_C116977 @default.
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• NCIT_C18115 type Class @default.
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• NCIT_C18115 label "Apoptosis Regulator Bcl-2" @default.
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