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- NCIT_C182005 IAO_0000115 "A human monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2; VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, pulocimab specifically binds to and inhibits VEGFR-2 on vascular endothelial cells, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR-2, a tyrosine-protein kinase that plays an essential role in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells, is overexpressed in certain tumor types." @default.
- NCIT_C182005 NCIT_A7 NCIT_C28496 @default.
- NCIT_C182005 NCIT_NHC0 "C182005" @default.
- NCIT_C182005 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C182005 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C182005 NCIT_P108 "Pulocimab" @default.
- NCIT_C182005 NCIT_P208 "CL1664826" @default.
- NCIT_C182005 NCIT_P210 "2428381-49-9" @default.
- NCIT_C182005 NCIT_P319 "FDL8DA4XV4" @default.
- NCIT_C182005 NCIT_P322 "FDA" @default.
- NCIT_C182005 NCIT_P322 "GDC" @default.
- NCIT_C182005 NCIT_P399 "806128" @default.
- NCIT_C182005 NCIT_R124 NCIT_C17710 @default.
- NCIT_C182005 NCIT_R124 NCIT_C17828 @default.
- NCIT_C182005 NCIT_R124 NCIT_C18219 @default.
- NCIT_C182005 NCIT_R124 NCIT_C19986 @default.
- NCIT_C182005 NCIT_R124 NCIT_C40474 @default.
- NCIT_C182005 normalizedInformationContent "100" @default.
- NCIT_C182005 referenceCount "1" @default.
- NCIT_C182005 hasExactSynonym "AK 109" @default.
- NCIT_C182005 hasExactSynonym "AK-109" @default.
- NCIT_C182005 hasExactSynonym "AK109" @default.
- NCIT_C182005 hasExactSynonym "Anti-VEGFR-2 Monoclonal Antibody AK109" @default.
- NCIT_C182005 hasExactSynonym "Anti-VEGFR2 Monoclonal Antibody AK109" @default.
- NCIT_C182005 hasExactSynonym "PULOCIMAB" @default.
- NCIT_C182005 hasExactSynonym "Pulocimab" @default.
- NCIT_C182005 inSubset NCIT_C128784 @default.
- NCIT_C182005 inSubset NCIT_C157711 @default.
- NCIT_C182005 inSubset NCIT_C157712 @default.
- NCIT_C182005 inSubset NCIT_C176424 @default.
- NCIT_C182005 inSubset NCIT_C63923 @default.
- NCIT_C182005 type Class @default.
- NCIT_C182005 isDefinedBy ncit.owl @default.
- NCIT_C182005 label "Pulocimab" @default.
- NCIT_C182005 subClassOf NCIT_C129821 @default.
- NCIT_C182005 subClassOf NCIT_C129822 @default.
- NCIT_C182005 subClassOf NCIT_C163758 @default.
- NCIT_C182005 subClassOf NCIT_C163953 @default.
- NCIT_C182005 subClassOf NCIT_C1742 @default.
- NCIT_C182005 subClassOf NCIT_C182005 @default.
- NCIT_C182005 subClassOf NCIT_C1908 @default.
- NCIT_C182005 subClassOf NCIT_C1909 @default.
- NCIT_C182005 subClassOf NCIT_C20401 @default.
- NCIT_C182005 subClassOf NCIT_C274 @default.
- NCIT_C182005 subClassOf NCIT_C307 @default.
- NCIT_C182005 subClassOf NCIT_C308 @default.
- NCIT_C182005 subClassOf NCIT_C93170 @default.