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- NCIT_C182008 IAO_0000115 "An orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities. Upon oral administration, Bcl-2 inhibitor TQB3909 targets, binds to and inhibits the activity of Bcl-2. This restores caspase-mediated apoptosis in tumor cells. Bcl-2 is overexpressed in many cancers and plays an important role in the negative regulation of apoptosis. Its expression is associated with increased drug resistance and tumor cell survival." @default.
- NCIT_C182008 NCIT_A7 NCIT_C153109 @default.
- NCIT_C182008 NCIT_NHC0 "C182008" @default.
- NCIT_C182008 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C182008 NCIT_P108 "Bcl-2 Inhibitor TQB3909" @default.
- NCIT_C182008 NCIT_P208 "CL1664813" @default.
- NCIT_C182008 NCIT_P322 "GDC" @default.
- NCIT_C182008 NCIT_P399 "806113" @default.
- NCIT_C182008 normalizedInformationContent "100" @default.
- NCIT_C182008 referenceCount "1" @default.
- NCIT_C182008 hasExactSynonym "Bcl-2 Inhibitor TQB3909" @default.
- NCIT_C182008 hasExactSynonym "TQB 3909" @default.
- NCIT_C182008 hasExactSynonym "TQB-3909" @default.
- NCIT_C182008 hasExactSynonym "TQB3909" @default.
- NCIT_C182008 inSubset NCIT_C128784 @default.
- NCIT_C182008 inSubset NCIT_C157711 @default.
- NCIT_C182008 inSubset NCIT_C157712 @default.
- NCIT_C182008 inSubset NCIT_C176424 @default.
- NCIT_C182008 type Class @default.
- NCIT_C182008 isDefinedBy ncit.owl @default.
- NCIT_C182008 label "Bcl-2 Inhibitor TQB3909" @default.
- NCIT_C182008 subClassOf NCIT_C129839 @default.
- NCIT_C182008 subClassOf NCIT_C159200 @default.
- NCIT_C182008 subClassOf NCIT_C163758 @default.
- NCIT_C182008 subClassOf NCIT_C182008 @default.
- NCIT_C182008 subClassOf NCIT_C1908 @default.
- NCIT_C182008 subClassOf NCIT_C1909 @default.
- NCIT_C182008 subClassOf NCIT_C192025 @default.
- NCIT_C182008 subClassOf NCIT_C274 @default.