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- NCIT_C182098 IAO_0000115 "A neutralizing human monoclonal antibody directed against the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for immunization against Coronavirus disease 2019 (COVID-19). Upon administration, plutavimab specifically targets and binds to the S1 subunit of the SARS-CoV-2 S protein, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus. The potency of STI-2020 was enhanced by an affinity maturation process." @default.
- NCIT_C182098 NCIT_A7 NCIT_C178209 @default.
- NCIT_C182098 NCIT_NHC0 "C182098" @default.
- NCIT_C182098 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C182098 NCIT_P108 "Plutavimab" @default.
- NCIT_C182098 NCIT_P208 "CL1770593" @default.
- NCIT_C182098 NCIT_P210 "2529854-88-2" @default.
- NCIT_C182098 NCIT_P319 "12U14K0SR5" @default.
- NCIT_C182098 NCIT_P322 "FDA" @default.
- NCIT_C182098 NCIT_R124 NCIT_C17710 @default.
- NCIT_C182098 NCIT_R124 NCIT_C17828 @default.
- NCIT_C182098 NCIT_R124 NCIT_C18219 @default.
- NCIT_C182098 NCIT_R124 NCIT_C19986 @default.
- NCIT_C182098 NCIT_R124 NCIT_C40474 @default.
- NCIT_C182098 normalizedInformationContent "100" @default.
- NCIT_C182098 referenceCount "1" @default.
- NCIT_C182098 hasExactSynonym "Affinity Matured COVI-GUARD" @default.
- NCIT_C182098 hasExactSynonym "Anti-SARS-CoV-2 S Protein Monoclonal Antibody STI-2020" @default.
- NCIT_C182098 hasExactSynonym "Anti-SARS-CoV-2 Spike Protein Monoclonal Antibody STI-2020" @default.
- NCIT_C182098 hasExactSynonym "COVI-AMG" @default.
- NCIT_C182098 hasExactSynonym "PLUTAVIMAB" @default.
- NCIT_C182098 hasExactSynonym "Plutavimab" @default.
- NCIT_C182098 hasExactSynonym "STI 2020" @default.
- NCIT_C182098 hasExactSynonym "STI-2020" @default.
- NCIT_C182098 hasExactSynonym "STI-2099" @default.
- NCIT_C182098 hasExactSynonym "STI2020" @default.
- NCIT_C182098 hasExactSynonym "STI2099" @default.
- NCIT_C182098 inSubset NCIT_C173381 @default.
- NCIT_C182098 inSubset NCIT_C173383 @default.
- NCIT_C182098 inSubset NCIT_C63923 @default.
- NCIT_C182098 type Class @default.
- NCIT_C182098 isDefinedBy ncit.owl @default.
- NCIT_C182098 label "Plutavimab" @default.
- NCIT_C182098 subClassOf NCIT_C173741 @default.
- NCIT_C182098 subClassOf NCIT_C182098 @default.
- NCIT_C182098 subClassOf NCIT_C1908 @default.
- NCIT_C182098 subClassOf NCIT_C1909 @default.
- NCIT_C182098 subClassOf NCIT_C20401 @default.
- NCIT_C182098 subClassOf NCIT_C307 @default.
- NCIT_C182098 subClassOf NCIT_C308 @default.