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- NCIT_C182103 IAO_0000115 "A vaccine consisting of a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding a full-length version of the spike (S) protein of SARS-CoV-2, with potential immunizing activity against SARS-CoV-2. Upon administration of the LNP-encapsulated SARS-CoV-2 mRNA vaccine PTX-COVID19-B, the lipid nanoparticle binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection." @default.
- NCIT_C182103 NCIT_NHC0 "C182103" @default.
- NCIT_C182103 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C182103 NCIT_P108 "Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B" @default.
- NCIT_C182103 NCIT_P208 "CL1770601" @default.
- NCIT_C182103 normalizedInformationContent "100" @default.
- NCIT_C182103 referenceCount "1" @default.
- NCIT_C182103 hasExactSynonym "LNP-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B" @default.
- NCIT_C182103 hasExactSynonym "Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B" @default.
- NCIT_C182103 hasExactSynonym "PTX-COVID19-B" @default.
- NCIT_C182103 inSubset NCIT_C173381 @default.
- NCIT_C182103 inSubset NCIT_C173383 @default.
- NCIT_C182103 type Class @default.
- NCIT_C182103 isDefinedBy ncit.owl @default.
- NCIT_C182103 label "Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B" @default.
- NCIT_C182103 subClassOf NCIT_C172787 @default.
- NCIT_C182103 subClassOf NCIT_C173023 @default.
- NCIT_C182103 subClassOf NCIT_C181140 @default.
- NCIT_C182103 subClassOf NCIT_C182103 @default.
- NCIT_C182103 subClassOf NCIT_C1908 @default.
- NCIT_C182103 subClassOf NCIT_C1909 @default.
- NCIT_C182103 subClassOf NCIT_C307 @default.
- NCIT_C182103 subClassOf NCIT_C308 @default.
- NCIT_C182103 subClassOf NCIT_C923 @default.