Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1823> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- NCIT_C1823 IAO_0000115 "A recombinant form of the endogenous cytokine human interferon (IFN) beta-1a, with antiproliferative, antiviral and immunomodulating activities. Upon administration, interferon beta-1a targets and binds to specific type I IFN receptors, which eventually results in the transcription and translation of genes containing an interferon-specific response element and leads to the production of various anti-viral proteins and modulates the production of various immune-modulating proteins. This reduces the production of certain pro-inflammatory cytokines while upregulating the anti-inflammatory cytokine interleukin 10 (IL-10), upregulates the expression of major histocompatibility (MHC) I proteins which allows for increased presentation of peptides derived from viral antigens, and activates CD8+ T cells as well as other immune cells. Endogenous IFN-beta-1a is produced following viral infection and it plays a key role in innate immune response against viral pathogens." @default.
- NCIT_C1823 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1823 NCIT_NHC0 "C1823" @default.
- NCIT_C1823 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1823 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1823 NCIT_P107 "Interferon Beta-1A" @default.
- NCIT_C1823 NCIT_P108 "Interferon Beta-1A" @default.
- NCIT_C1823 NCIT_P207 "C0982234" @default.
- NCIT_C1823 NCIT_P210 "145258-61-3" @default.
- NCIT_C1823 NCIT_P302 "Multiple sclerosis" @default.
- NCIT_C1823 NCIT_P319 "XRO4566Q4R" @default.
- NCIT_C1823 NCIT_P322 "CTRP" @default.
- NCIT_C1823 NCIT_P322 "FDA" @default.
- NCIT_C1823 NCIT_P322 "GDC" @default.
- NCIT_C1823 NCIT_P366 "Interferon_Beta-1A" @default.
- NCIT_C1823 NCIT_P375 "Interferon Beta-1A" @default.
- NCIT_C1823 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1823 NCIT_R124 NCIT_C18992 @default.
- NCIT_C1823 NCIT_R124 NCIT_C19143 @default.
- NCIT_C1823 NCIT_R124 NCIT_C21124 @default.
- NCIT_C1823 NCIT_R124 NCIT_C40702 @default.
- NCIT_C1823 NCIT_R124 NCIT_C45547 @default.
- NCIT_C1823 NCIT_R125 NCIT_C17710 @default.
- NCIT_C1823 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1823 NCIT_R125 NCIT_C17937 @default.
- NCIT_C1823 NCIT_R125 NCIT_C18081 @default.
- NCIT_C1823 NCIT_R125 NCIT_C18095 @default.
- NCIT_C1823 NCIT_R125 NCIT_C18839 @default.
- NCIT_C1823 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1823 NCIT_R125 NCIT_C20751 @default.
- NCIT_C1823 NCIT_R125 NCIT_C21049 @default.
- NCIT_C1823 NCIT_R125 NCIT_C21050 @default.
- NCIT_C1823 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1823 NCIT_R125 NCIT_C28498 @default.
- NCIT_C1823 NCIT_R125 NCIT_C40912 @default.
- NCIT_C1823 NCIT_R146 NCIT_C21176 @default.
- NCIT_C1823 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1823 NCIT_R146 NCIT_C37274 @default.
- NCIT_C1823 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C1823 referenceCount "3" @default.
- NCIT_C1823 hasExactSynonym "Avonex" @default.
- NCIT_C1823 hasExactSynonym "BG9418" @default.
- NCIT_C1823 hasExactSynonym "INTERFERON BETA-1A" @default.
- NCIT_C1823 hasExactSynonym "Interferon Beta-1A" @default.
- NCIT_C1823 hasExactSynonym "Rebif" @default.
- NCIT_C1823 hasExactSynonym "Recombinant interferon beta-1a" @default.
- NCIT_C1823 inSubset NCIT_C116977 @default.
- NCIT_C1823 inSubset NCIT_C116978 @default.
- NCIT_C1823 inSubset NCIT_C128784 @default.
- NCIT_C1823 inSubset NCIT_C157711 @default.
- NCIT_C1823 inSubset NCIT_C157712 @default.
- NCIT_C1823 inSubset NCIT_C173381 @default.
- NCIT_C1823 inSubset NCIT_C173383 @default.
- NCIT_C1823 inSubset NCIT_C177537 @default.
- NCIT_C1823 inSubset NCIT_C63923 @default.
- NCIT_C1823 type Class @default.
- NCIT_C1823 isDefinedBy ncit.owl @default.
- NCIT_C1823 label "Interferon Beta-1A" @default.
- NCIT_C1823 subClassOf NCIT_C1283 @default.
- NCIT_C1823 subClassOf NCIT_C1823 @default.
- NCIT_C1823 subClassOf NCIT_C1908 @default.
- NCIT_C1823 subClassOf NCIT_C1909 @default.
- NCIT_C1823 subClassOf NCIT_C307 @default.
- NCIT_C1823 subClassOf NCIT_C308 @default.
- NCIT_C1823 subClassOf NCIT_C495 @default.
- NCIT_C1823 subClassOf NCIT_C584 @default.