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- NCIT_C182443 IAO_0000115 "Complement C3 beta chain (645 aa, ~71 kDa) is encoded by the human C3 gene. This protein is involved in binding to microbial surfaces, attachment to Fc regions of antigen-bound antibodies, opsonization, phagocytosis and complement activation. Uncontrolled generation of this protein fragment is associated with C3 glomerulopathy and atypical hemolytic uremic syndrome (aHUS)." @default.
- NCIT_C182443 NCIT_NHC0 "C182443" @default.
- NCIT_C182443 NCIT_P100 "120700" @default.
- NCIT_C182443 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C182443 NCIT_P107 "Complement C3 Beta Chain" @default.
- NCIT_C182443 NCIT_P108 "Complement C3 Beta Chain" @default.
- NCIT_C182443 NCIT_P208 "CL1771130" @default.
- NCIT_C182443 NCIT_P322 "CTRP" @default.
- NCIT_C182443 NCIT_P93 "P01024" @default.
- NCIT_C182443 NCIT_P98 "Complement C3 beta chain (C3b) is comprised of amino acids 23-667 of complement C3 and is produced through proteolysis of complement C3 into a C-terminal alpha chain and a N-terminal beta chain (C3b). C3b can bind to complement factor B to form C3 convertase. When C3b bind to C4b and C2b (C4b2b3b complex) or when a second C3b molecule binds to the C3bBb complex (C3bBb3b complex) the C5 convertase is formed." @default.
- NCIT_C182443 NCIT_R131 NCIT_C19779 @default.
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- NCIT_C182443 NCIT_R53 NCIT_C21519 @default.
- NCIT_C182443 NCIT_R53 NCIT_C28498 @default.
- NCIT_C182443 NCIT_R54 NCIT_C16612 @default.
- NCIT_C182443 NCIT_R54 NCIT_C21518 @default.
- NCIT_C182443 NCIT_R54 NCIT_C21521 @default.
- NCIT_C182443 normalizedInformationContent "100" @default.
- NCIT_C182443 referenceCount "1" @default.
- NCIT_C182443 hasExactSynonym "C3b" @default.
- NCIT_C182443 hasExactSynonym "Complement C3 Beta Chain" @default.
- NCIT_C182443 hasExactSynonym "Complement C3b" @default.
- NCIT_C182443 hasExactSynonym "Complement Component C3b" @default.
- NCIT_C182443 inSubset NCIT_C116977 @default.
- NCIT_C182443 inSubset NCIT_C142799 @default.
- NCIT_C182443 inSubset NCIT_C142800 @default.
- NCIT_C182443 type Class @default.
- NCIT_C182443 isDefinedBy ncit.owl @default.
- NCIT_C182443 label "Complement C3 Beta Chain" @default.
- NCIT_C182443 subClassOf NCIT_C154098 @default.
- NCIT_C182443 subClassOf NCIT_C17021 @default.
- NCIT_C182443 subClassOf NCIT_C182443 @default.
- NCIT_C182443 subClassOf NCIT_C20027 @default.
- NCIT_C182443 subClassOf NCIT_C21523 @default.
- NCIT_C182443 subClassOf NCIT_C26548 @default.
- NCIT_C182443 equivalentClass B09a07e10619c4fdc31e7baf9b0797ce8 @default.
- NCIT_C182443 equivalentClass B6da137bad4b2d4610780fc68be391fc9 @default.