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- NCIT_C1831 IAO_0000115 "A quinolone derivative with potential antineoplastic activity. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature. This agent also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells." @default.
- NCIT_C1831 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1831 NCIT_A7 NCIT_C17328 @default.
- NCIT_C1831 NCIT_A7 NCIT_C28496 @default.
- NCIT_C1831 NCIT_NHC0 "C1831" @default.
- NCIT_C1831 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1831 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1831 NCIT_P107 "Semaxanib" @default.
- NCIT_C1831 NCIT_P108 "Semaxanib" @default.
- NCIT_C1831 NCIT_P175 "696819" @default.
- NCIT_C1831 NCIT_P207 "C1135174" @default.
- NCIT_C1831 NCIT_P210 "194413-58-6" @default.
- NCIT_C1831 NCIT_P319 "71IA9S35AJ" @default.
- NCIT_C1831 NCIT_P322 "CTRP" @default.
- NCIT_C1831 NCIT_P322 "FDA" @default.
- NCIT_C1831 NCIT_P322 "GDC" @default.
- NCIT_C1831 NCIT_P325 "A substance that has been studied in the treatment of cancer. It belongs to the families of drugs called angiogenesis inhibitors and tyrosine kinase inhibitors." @default.
- NCIT_C1831 NCIT_P329 "43310" @default.
- NCIT_C1831 NCIT_P330 "43310" @default.
- NCIT_C1831 NCIT_P350 "C15H14N2O" @default.
- NCIT_C1831 NCIT_P366 "Semaxanib" @default.
- NCIT_C1831 NCIT_P375 "Semaxanib" @default.
- NCIT_C1831 NCIT_P399 "43310" @default.
- NCIT_C1831 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1831 NCIT_R124 NCIT_C18992 @default.
- NCIT_C1831 NCIT_R124 NCIT_C19143 @default.
- NCIT_C1831 NCIT_R124 NCIT_C21124 @default.
- NCIT_C1831 NCIT_R124 NCIT_C40702 @default.
- NCIT_C1831 NCIT_R124 NCIT_C40703 @default.
- NCIT_C1831 NCIT_R125 NCIT_C17710 @default.
- NCIT_C1831 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1831 NCIT_R125 NCIT_C17932 @default.
- NCIT_C1831 NCIT_R125 NCIT_C18081 @default.
- NCIT_C1831 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1831 NCIT_R125 NCIT_C20751 @default.
- NCIT_C1831 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1831 NCIT_R125 NCIT_C21128 @default.
- NCIT_C1831 NCIT_R125 NCIT_C21147 @default.
- NCIT_C1831 NCIT_R125 NCIT_C26044 @default.
- NCIT_C1831 NCIT_R125 NCIT_C28498 @default.
- NCIT_C1831 NCIT_R125 NCIT_C40576 @default.
- NCIT_C1831 NCIT_R125 NCIT_C40577 @default.
- NCIT_C1831 NCIT_R146 NCIT_C141266 @default.
- NCIT_C1831 NCIT_R146 NCIT_C16554 @default.
- NCIT_C1831 NCIT_R146 NCIT_C16984 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17018 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17020 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17021 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17210 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17328 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17660 @default.
- NCIT_C1831 NCIT_R146 NCIT_C17728 @default.
- NCIT_C1831 NCIT_R146 NCIT_C18106 @default.
- NCIT_C1831 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1831 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1831 NCIT_R146 NCIT_C28496 @default.
- NCIT_C1831 NCIT_R72 NCIT_C12219 @default.
- NCIT_C1831 NCIT_R72 NCIT_C12471 @default.
- NCIT_C1831 NCIT_R72 NCIT_C12481 @default.
- NCIT_C1831 NCIT_R72 NCIT_C12801 @default.
- NCIT_C1831 NCIT_R72 NCIT_C12964 @default.
- NCIT_C1831 NCIT_R72 NCIT_C13053 @default.
- NCIT_C1831 normalizedInformationContent "82.536929774922015" @default.
- NCIT_C1831 referenceCount "14" @default.
- NCIT_C1831 hasExactSynonym "H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-" @default.
- NCIT_C1831 hasExactSynonym "SEMAXANIB" @default.
- NCIT_C1831 hasExactSynonym "SU 5416" @default.
- NCIT_C1831 hasExactSynonym "SU5416" @default.
- NCIT_C1831 hasExactSynonym "Semaxanib" @default.
- NCIT_C1831 hasExactSynonym "Semoxind" @default.
- NCIT_C1831 hasExactSynonym "Sugen 5416" @default.
- NCIT_C1831 hasExactSynonym "semaxanib" @default.
- NCIT_C1831 inSubset NCIT_C116977 @default.
- NCIT_C1831 inSubset NCIT_C116978 @default.
- NCIT_C1831 inSubset NCIT_C128784 @default.
- NCIT_C1831 inSubset NCIT_C157711 @default.
- NCIT_C1831 inSubset NCIT_C157712 @default.
- NCIT_C1831 inSubset NCIT_C176424 @default.
- NCIT_C1831 inSubset NCIT_C177537 @default.
- NCIT_C1831 inSubset NCIT_C63923 @default.
- NCIT_C1831 type Class @default.
- NCIT_C1831 isDefinedBy ncit.owl @default.
- NCIT_C1831 label "Semaxanib" @default.
- NCIT_C1831 subClassOf NCIT_C1404 @default.
- NCIT_C1831 subClassOf NCIT_C1742 @default.
- NCIT_C1831 subClassOf NCIT_C1831 @default.
- NCIT_C1831 subClassOf NCIT_C1908 @default.
- NCIT_C1831 subClassOf NCIT_C1909 @default.
- NCIT_C1831 subClassOf NCIT_C1967 @default.
- NCIT_C1831 subClassOf NCIT_C274 @default.
- NCIT_C1831 subClassOf NCIT_C471 @default.
- NCIT_C1831 equivalentClass B5db104c3b9f8ded2fe144e694398e8b1 @default.
- NCIT_C1831 equivalentClass B9fe18d80958d1d51e2e431e18b06915a @default.