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- NCIT_C183131 IAO_0000115 "The hydrochloride salt of a synthetic quinazoline derivative, Anagrelide Hydrochloride reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)" @default.
- NCIT_C183131 NCIT_A6 NCIT_C28825 @default.
- NCIT_C183131 NCIT_NHC0 "C183131" @default.
- NCIT_C183131 NCIT_P106 "Organic Chemical" @default.
- NCIT_C183131 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C183131 NCIT_P108 "Anagrelide Hydrochloride" @default.
- NCIT_C183131 NCIT_P207 "C0771907" @default.
- NCIT_C183131 NCIT_P210 "823178-43-4" @default.
- NCIT_C183131 NCIT_P319 "YTM763Y5C8" @default.
- NCIT_C183131 NCIT_P322 "FDA" @default.
- NCIT_C183131 NCIT_P366 "Anagrelide_Hydrochloride" @default.
- NCIT_C183131 normalizedInformationContent "100" @default.
- NCIT_C183131 referenceCount "1" @default.
- NCIT_C183131 hasExactSynonym "ANAGRELIDE HYDROCHLORIDE" @default.
- NCIT_C183131 hasExactSynonym "Agrylin" @default.
- NCIT_C183131 hasExactSynonym "Anagrelide Hydrochloride" @default.
- NCIT_C183131 hasExactSynonym "BL-4162A" @default.
- NCIT_C183131 hasExactSynonym "BMY-26538-01" @default.
- NCIT_C183131 inSubset NCIT_C63923 @default.
- NCIT_C183131 type Class @default.
- NCIT_C183131 isDefinedBy ncit.owl @default.
- NCIT_C183131 label "Anagrelide Hydrochloride" @default.
- NCIT_C183131 subClassOf NCIT_C1327 @default.
- NCIT_C183131 subClassOf NCIT_C183131 @default.
- NCIT_C183131 subClassOf NCIT_C1908 @default.
- NCIT_C183131 subClassOf NCIT_C1909 @default.
- NCIT_C183131 subClassOf NCIT_C78275 @default.