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- NCIT_C183335 IAO_0000115 "A vaccine composed of a replication-deficient chimpanzee adenovirus, ChAdOx1, encoding the spike (S) glycoprotein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) beta (B.1.351, South African) variant, with potential immunomodulating and anti-viral activities. Upon administration, ChAdOx1-vectored COVID-19 variant vaccine AZD2816 expresses the SARS-CoV-2 beta variant S protein, which contains ten changes across the S protein. This induces a humoral and cell-mediated immune response against SARS-CoV-2, and may prevent SARS-CoV-2 infection and inhibit viral replication. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus. AZD2816 may induce neutralizing antibodies against SARS-CoV-2 variants including beta, gamma (P.1) and delta (B.1.617.2)." @default.
- NCIT_C183335 NCIT_NHC0 "C183335" @default.
- NCIT_C183335 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C183335 NCIT_P108 "ChAdOx1-vectored COVID-19 Variant Vaccine AZD2816" @default.
- NCIT_C183335 NCIT_P208 "CL1771597" @default.
- NCIT_C183335 normalizedInformationContent "100" @default.
- NCIT_C183335 referenceCount "1" @default.
- NCIT_C183335 hasExactSynonym "AZD 2816" @default.
- NCIT_C183335 hasExactSynonym "AZD-2816" @default.
- NCIT_C183335 hasExactSynonym "AZD2816" @default.
- NCIT_C183335 hasExactSynonym "B.1.351 Vaccine AZD2816" @default.
- NCIT_C183335 hasExactSynonym "ChAdOx1-vectored COVID-19 Variant Vaccine AZD2816" @default.
- NCIT_C183335 hasExactSynonym "SARS-CoV-2 Vaccine AZD2816" @default.
- NCIT_C183335 inSubset NCIT_C173381 @default.
- NCIT_C183335 inSubset NCIT_C173383 @default.
- NCIT_C183335 type Class @default.
- NCIT_C183335 isDefinedBy ncit.owl @default.
- NCIT_C183335 label "ChAdOx1-vectored COVID-19 Variant Vaccine AZD2816" @default.
- NCIT_C183335 subClassOf NCIT_C1572 @default.
- NCIT_C183335 subClassOf NCIT_C173023 @default.
- NCIT_C183335 subClassOf NCIT_C183335 @default.
- NCIT_C183335 subClassOf NCIT_C1908 @default.
- NCIT_C183335 subClassOf NCIT_C1909 @default.
- NCIT_C183335 subClassOf NCIT_C307 @default.
- NCIT_C183335 subClassOf NCIT_C308 @default.
- NCIT_C183335 subClassOf NCIT_C923 @default.
- NCIT_C183335 subClassOf NCIT_C96404 @default.