Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C18334> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- NCIT_C18334 IAO_0000115 "Human Oncogene LCK is a mutated variant of LCK Gene, which encodes p56LCK, a lymphocyte-specific tyrosine protein kinase with an SH2 and SH3 domain. LCK may participate in T-cell activation; p56LCK regulates allelic exclusion at the TCR beta locus. It binds to CD4, CD8 and IL-2R beta chain cytoplasmic domains. p56LCK is quickly activated by mIg cross-linking on B-cells or by TCR cross-linking. Pre-TCR co-localizes with p56LCK kinase in membrane rafts resulting in phosphorylation of CD3-epsilon and ZAP70. p56LCK, in the TCR complex, activates DNA binding of STAT5A and STAT5B. Oncogene LCK disrupts normal cell function." @default.
- NCIT_C18334 NCIT_NHC0 "C18334" @default.
- NCIT_C18334 NCIT_P100 "153390" @default.
- NCIT_C18334 NCIT_P102 "M36881" @default.
- NCIT_C18334 NCIT_P106 "Gene or Genome" @default.
- NCIT_C18334 NCIT_P108 "Oncogene LCK" @default.
- NCIT_C18334 NCIT_P208 "CL448408" @default.
- NCIT_C18334 NCIT_P366 "Oncogene_LCK" @default.
- NCIT_C18334 NCIT_R155 NCIT_C12219 @default.
- NCIT_C18334 NCIT_R155 NCIT_C13282 @default.
- NCIT_C18334 NCIT_R155 NCIT_C13377 @default.
- NCIT_C18334 NCIT_R155 NCIT_C13432 @default.
- NCIT_C18334 NCIT_R155 NCIT_C13446 @default.
- NCIT_C18334 NCIT_R155 NCIT_C13573 @default.
- NCIT_C18334 NCIT_R155 NCIT_C14135 @default.
- NCIT_C18334 NCIT_R155 NCIT_C32221 @default.
- NCIT_C18334 NCIT_R155 NCIT_C34070 @default.
- NCIT_C18334 NCIT_R37 NCIT_C16956 @default.
- NCIT_C18334 NCIT_R37 NCIT_C16983 @default.
- NCIT_C18334 NCIT_R37 NCIT_C17019 @default.
- NCIT_C18334 NCIT_R37 NCIT_C17133 @default.
- NCIT_C18334 NCIT_R37 NCIT_C17710 @default.
- NCIT_C18334 NCIT_R37 NCIT_C17828 @default.
- NCIT_C18334 NCIT_R37 NCIT_C18121 @default.
- NCIT_C18334 NCIT_R37 NCIT_C18264 @default.
- NCIT_C18334 NCIT_R37 NCIT_C18496 @default.
- NCIT_C18334 NCIT_R37 NCIT_C19406 @default.
- NCIT_C18334 NCIT_R37 NCIT_C19536 @default.
- NCIT_C18334 NCIT_R37 NCIT_C19899 @default.
- NCIT_C18334 NCIT_R37 NCIT_C19903 @default.
- NCIT_C18334 NCIT_R37 NCIT_C20480 @default.
- NCIT_C18334 NCIT_R37 NCIT_C21188 @default.
- NCIT_C18334 NCIT_R37 NCIT_C21198 @default.
- NCIT_C18334 NCIT_R37 NCIT_C28498 @default.
- NCIT_C18334 NCIT_R40 NCIT_C12219 @default.
- NCIT_C18334 NCIT_R40 NCIT_C13282 @default.
- NCIT_C18334 NCIT_R40 NCIT_C13377 @default.
- NCIT_C18334 NCIT_R40 NCIT_C13432 @default.
- NCIT_C18334 NCIT_R40 NCIT_C13446 @default.
- NCIT_C18334 NCIT_R40 NCIT_C13573 @default.
- NCIT_C18334 NCIT_R40 NCIT_C14135 @default.
- NCIT_C18334 NCIT_R40 NCIT_C32221 @default.
- NCIT_C18334 NCIT_R40 NCIT_C34070 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14182 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14225 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14234 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14250 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14262 @default.
- NCIT_C18334 NCIT_R41 NCIT_C14282 @default.
- NCIT_C18334 NCIT_R41 NCIT_C25796 @default.
- NCIT_C18334 NCIT_R41 NCIT_C79740 @default.
- NCIT_C18334 normalizedInformationContent "100" @default.
- NCIT_C18334 referenceCount "1" @default.
- NCIT_C18334 hasExactSynonym "Oncogene LCK" @default.
- NCIT_C18334 type Class @default.
- NCIT_C18334 isDefinedBy ncit.owl @default.
- NCIT_C18334 label "Oncogene LCK" @default.
- NCIT_C18334 subClassOf NCIT_C16612 @default.
- NCIT_C18334 subClassOf NCIT_C16936 @default.
- NCIT_C18334 subClassOf NCIT_C18334 @default.
- NCIT_C18334 subClassOf NCIT_C18343 @default.
- NCIT_C18334 subClassOf NCIT_C18344 @default.
- NCIT_C18334 subClassOf NCIT_C18540 @default.
- NCIT_C18334 subClassOf NCIT_C19540 @default.
- NCIT_C18334 equivalentClass B6cc02f68040d3d8bdb15b5625b6fe0d6 @default.
- NCIT_C18334 equivalentClass Bd75279561d899ea7bb1406f1d03b94a6 @default.