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- NCIT_C184369 IAO_0000115 "A bispecific monoclonal antibody targeting CD3, a T-cell surface antigen, and CD38, a human cell surface glycoprotein and tumor-associated antigen (TAA), with potential antineoplastic activity. Upon administration, anti-CD3/CD38 bispecific monoclonal antibody XmAb18968 binds to both CD3 on T-cells and CD38 expressed on tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against CD38-expressing tumor cells. CD38, a type II transmembrane glycoprotein, is present on various immune cells and hematologic malignancies; its expression has been correlated with poor prognosis." @default.
- NCIT_C184369 NCIT_A7 NCIT_C84323 @default.
- NCIT_C184369 NCIT_NHC0 "C184369" @default.
- NCIT_C184369 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C184369 NCIT_P107 "Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 NCIT_P108 "Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 NCIT_P208 "CL1772550" @default.
- NCIT_C184369 NCIT_P322 "CTRP" @default.
- NCIT_C184369 NCIT_P322 "GDC" @default.
- NCIT_C184369 NCIT_P399 "806938" @default.
- NCIT_C184369 NCIT_R124 NCIT_C17710 @default.
- NCIT_C184369 NCIT_R124 NCIT_C17828 @default.
- NCIT_C184369 NCIT_R124 NCIT_C18219 @default.
- NCIT_C184369 NCIT_R124 NCIT_C19986 @default.
- NCIT_C184369 NCIT_R124 NCIT_C40474 @default.
- NCIT_C184369 normalizedInformationContent "100" @default.
- NCIT_C184369 referenceCount "1" @default.
- NCIT_C184369 hasExactSynonym "Anti-CD3/CD38 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 hasExactSynonym "Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 hasExactSynonym "CD3 x CD38 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 hasExactSynonym "XmAb 18968" @default.
- NCIT_C184369 hasExactSynonym "XmAb-18968" @default.
- NCIT_C184369 hasExactSynonym "XmAb18968" @default.
- NCIT_C184369 inSubset NCIT_C116977 @default.
- NCIT_C184369 inSubset NCIT_C116978 @default.
- NCIT_C184369 inSubset NCIT_C128784 @default.
- NCIT_C184369 inSubset NCIT_C157711 @default.
- NCIT_C184369 inSubset NCIT_C157712 @default.
- NCIT_C184369 inSubset NCIT_C176424 @default.
- NCIT_C184369 type Class @default.
- NCIT_C184369 isDefinedBy ncit.owl @default.
- NCIT_C184369 label "Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968" @default.
- NCIT_C184369 subClassOf NCIT_C112883 @default.
- NCIT_C184369 subClassOf NCIT_C129821 @default.
- NCIT_C184369 subClassOf NCIT_C129822 @default.
- NCIT_C184369 subClassOf NCIT_C1454 @default.
- NCIT_C184369 subClassOf NCIT_C155321 @default.
- NCIT_C184369 subClassOf NCIT_C163758 @default.
- NCIT_C184369 subClassOf NCIT_C164008 @default.
- NCIT_C184369 subClassOf NCIT_C184369 @default.
- NCIT_C184369 subClassOf NCIT_C1908 @default.
- NCIT_C184369 subClassOf NCIT_C1909 @default.
- NCIT_C184369 subClassOf NCIT_C201282 @default.
- NCIT_C184369 subClassOf NCIT_C20401 @default.
- NCIT_C184369 subClassOf NCIT_C274 @default.
- NCIT_C184369 subClassOf NCIT_C28227 @default.
- NCIT_C184369 subClassOf NCIT_C307 @default.
- NCIT_C184369 subClassOf NCIT_C308 @default.