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- NCIT_C1845 IAO_0000115 "A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological activity of this agent is derived from its interferon alpha-2b protein moiety. Interferons alfa bind to specific cell-surface receptors, leading to the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. The PEG moiety lowers the clearance of interferon alpha-2b, thereby extending the duration of its therapeutic effects, but may also reduce the interferon-mediated stimulation of an immune response. (NCI04)" @default.
- NCIT_C1845 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1845 NCIT_NHC0 "C1845" @default.
- NCIT_C1845 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1845 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C1845 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1845 NCIT_P107 "Peginterferon Alfa-2b" @default.
- NCIT_C1845 NCIT_P108 "Peginterferon Alfa-2b" @default.
- NCIT_C1845 NCIT_P175 "720033" @default.
- NCIT_C1845 NCIT_P207 "C0796545" @default.
- NCIT_C1845 NCIT_P210 "215647-85-1" @default.
- NCIT_C1845 NCIT_P302 "chronic hepatitis C; renal cell carcinoma" @default.
- NCIT_C1845 NCIT_P319 "G8RGG88B68" @default.
- NCIT_C1845 NCIT_P322 "CTRP" @default.
- NCIT_C1845 NCIT_P322 "FDA" @default.
- NCIT_C1845 NCIT_P322 "GDC" @default.
- NCIT_C1845 NCIT_P325 "A drug used to treat hepatitis C infections. It is also being studied in the treatment and prevention of cancer. It is a cytokine that is modified in the laboratory. It is a type of biological response modifier." @default.
- NCIT_C1845 NCIT_P329 "43407" @default.
- NCIT_C1845 NCIT_P330 "43407" @default.
- NCIT_C1845 NCIT_P350 "C2H4NO2(C2H4O)n" @default.
- NCIT_C1845 NCIT_P366 "PEG-Interferon_Alfa-2B" @default.
- NCIT_C1845 NCIT_P368 "CHEBI:63615" @default.
- NCIT_C1845 NCIT_P375 "Peginterferon Alfa-2b" @default.
- NCIT_C1845 NCIT_P399 "43407" @default.
- NCIT_C1845 normalizedInformationContent "84.76342111748103" @default.
- NCIT_C1845 referenceCount "10" @default.
- NCIT_C1845 hasExactSynonym "PEG Interferon Alpha-2b" @default.
- NCIT_C1845 hasExactSynonym "PEG Intron" @default.
- NCIT_C1845 hasExactSynonym "PEG-IFN Alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "PEG-IFN-a 2b" @default.
- NCIT_C1845 hasExactSynonym "PEG-Interferon Alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "PEG-Intron" @default.
- NCIT_C1845 hasExactSynonym "PEG-interferon alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "PEGINTERFERON ALFA-2B" @default.
- NCIT_C1845 hasExactSynonym "PegIntron" @default.
- NCIT_C1845 hasExactSynonym "Peginterferon Alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "Pegylated Interferon Alpha-2b" @default.
- NCIT_C1845 hasExactSynonym "Pegylated Interferon alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "Polyethylene Glycol IFN-A2b" @default.
- NCIT_C1845 hasExactSynonym "Polyethylene Glycol Interferon Alfa-2b" @default.
- NCIT_C1845 hasExactSynonym "SCH 54031" @default.
- NCIT_C1845 hasExactSynonym "Sylatron" @default.
- NCIT_C1845 inSubset NCIT_C116977 @default.
- NCIT_C1845 inSubset NCIT_C116978 @default.
- NCIT_C1845 inSubset NCIT_C128784 @default.
- NCIT_C1845 inSubset NCIT_C157711 @default.
- NCIT_C1845 inSubset NCIT_C157712 @default.
- NCIT_C1845 inSubset NCIT_C173381 @default.
- NCIT_C1845 inSubset NCIT_C173383 @default.
- NCIT_C1845 inSubset NCIT_C176424 @default.
- NCIT_C1845 inSubset NCIT_C177537 @default.
- NCIT_C1845 inSubset NCIT_C63923 @default.
- NCIT_C1845 type Class @default.
- NCIT_C1845 isDefinedBy ncit.owl @default.
- NCIT_C1845 label "Peginterferon Alfa-2b" @default.
- NCIT_C1845 subClassOf NCIT_C1283 @default.
- NCIT_C1845 subClassOf NCIT_C1742 @default.
- NCIT_C1845 subClassOf NCIT_C1845 @default.
- NCIT_C1845 subClassOf NCIT_C1908 @default.
- NCIT_C1845 subClassOf NCIT_C1909 @default.
- NCIT_C1845 subClassOf NCIT_C1971 @default.
- NCIT_C1845 subClassOf NCIT_C225 @default.
- NCIT_C1845 subClassOf NCIT_C2491 @default.
- NCIT_C1845 subClassOf NCIT_C274 @default.
- NCIT_C1845 subClassOf NCIT_C307 @default.
- NCIT_C1845 subClassOf NCIT_C308 @default.
- NCIT_C1845 subClassOf NCIT_C584 @default.