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- NCIT_C1848 IAO_0000115 "A sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis." @default.
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- NCIT_C1848 NCIT_A7 NCIT_C41029 @default.
- NCIT_C1848 NCIT_NHC0 "C1848" @default.
- NCIT_C1848 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1848 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1848 NCIT_P108 "Suramin Sodium" @default.
- NCIT_C1848 NCIT_P175 "34936" @default.
- NCIT_C1848 NCIT_P207 "C0813205" @default.
- NCIT_C1848 NCIT_P210 "129-46-4" @default.
- NCIT_C1848 NCIT_P302 "African trypanosomiasis; onchocerciasis" @default.
- NCIT_C1848 NCIT_P319 "89521262IH" @default.
- NCIT_C1848 NCIT_P322 "FDA" @default.
- NCIT_C1848 NCIT_P322 "GDC" @default.
- NCIT_C1848 NCIT_P329 "40052" @default.
- NCIT_C1848 NCIT_P330 "40052" @default.
- NCIT_C1848 NCIT_P350 "C51H34N6O23S6.6Na" @default.
- NCIT_C1848 NCIT_P366 "Suramin_Sodium" @default.
- NCIT_C1848 NCIT_P375 "Suramin Sodium" @default.
- NCIT_C1848 NCIT_P399 "40052" @default.
- NCIT_C1848 NCIT_R124 NCIT_C17828 @default.
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- NCIT_C1848 NCIT_R146 NCIT_C17021 @default.
- NCIT_C1848 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1848 NCIT_R146 NCIT_C20424 @default.
- NCIT_C1848 NCIT_R146 NCIT_C26548 @default.
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- NCIT_C1848 NCIT_R72 NCIT_C12219 @default.
- NCIT_C1848 NCIT_R72 NCIT_C12471 @default.
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- NCIT_C1848 NCIT_R72 NCIT_C12508 @default.
- NCIT_C1848 NCIT_R72 NCIT_C12555 @default.
- NCIT_C1848 NCIT_R72 NCIT_C12801 @default.
- NCIT_C1848 NCIT_R72 NCIT_C12865 @default.
- NCIT_C1848 NCIT_R72 NCIT_C12964 @default.
- NCIT_C1848 NCIT_R72 NCIT_C21599 @default.
- NCIT_C1848 normalizedInformationContent "100" @default.
- NCIT_C1848 referenceCount "1" @default.
- NCIT_C1848 hasExactSynonym "309 F" @default.
- NCIT_C1848 hasExactSynonym "8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-1,3,5-naphthalenetrisulfonic Acid Hexasodium Salt" @default.
- NCIT_C1848 hasExactSynonym "Antrypol" @default.
- NCIT_C1848 hasExactSynonym "Bayer 205" @default.
- NCIT_C1848 hasExactSynonym "Belganyl" @default.
- NCIT_C1848 hasExactSynonym "CI-1003" @default.
- NCIT_C1848 hasExactSynonym "Fourneau 309" @default.
- NCIT_C1848 hasExactSynonym "Germanin" @default.
- NCIT_C1848 hasExactSynonym "Metaret" @default.
- NCIT_C1848 hasExactSynonym "Moranyl" @default.
- NCIT_C1848 hasExactSynonym "Naganin" @default.
- NCIT_C1848 hasExactSynonym "Naganinum" @default.
- NCIT_C1848 hasExactSynonym "Naganol" @default.
- NCIT_C1848 hasExactSynonym "Naphuride" @default.
- NCIT_C1848 hasExactSynonym "SURAMIN SODIUM" @default.
- NCIT_C1848 hasExactSynonym "Sodium Suramin" @default.
- NCIT_C1848 hasExactSynonym "Sodium suramin" @default.
- NCIT_C1848 hasExactSynonym "Suramin Hexasodium" @default.
- NCIT_C1848 hasExactSynonym "Suramin Sodium" @default.
- NCIT_C1848 hasExactSynonym "Suramin sodium" @default.
- NCIT_C1848 inSubset NCIT_C128784 @default.
- NCIT_C1848 inSubset NCIT_C157711 @default.
- NCIT_C1848 inSubset NCIT_C157712 @default.
- NCIT_C1848 inSubset NCIT_C176424 @default.
- NCIT_C1848 inSubset NCIT_C177537 @default.
- NCIT_C1848 inSubset NCIT_C63923 @default.
- NCIT_C1848 type Class @default.
- NCIT_C1848 isDefinedBy ncit.owl @default.
- NCIT_C1848 label "Suramin Sodium" @default.
- NCIT_C1848 subClassOf B068444d3bf06b1517b8341a3e66ec4db @default.
- NCIT_C1848 subClassOf B117a0e8ad10c961ff9f315049fed90c0 @default.
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- NCIT_C1848 subClassOf NCIT_C1742 @default.
- NCIT_C1848 subClassOf NCIT_C1848 @default.
- NCIT_C1848 subClassOf NCIT_C1908 @default.
- NCIT_C1848 subClassOf NCIT_C1909 @default.
- NCIT_C1848 subClassOf NCIT_C1971 @default.
- NCIT_C1848 subClassOf NCIT_C274 @default.