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- NCIT_C185281 IAO_0000115 "An intrathecal (IT) formulation of deferoxamine (DFO), an iron-chelating agent that can be used to deplete free iron and lower iron levels, and with potential antineoplastic activity. Upon IT administration via Ommaya reservoir, DFO chelates free iron within the cerebrospinal fluid (CSF) by forming the iron complex ferrioxamine. This lowers the amount of iron available for cancer cell growth and survival. Cancer cells show increased iron uptake as iron is needed for rapid tumor cell proliferation." @default.
- NCIT_C185281 NCIT_A7 NCIT_C598 @default.
- NCIT_C185281 NCIT_NHC0 "C185281" @default.
- NCIT_C185281 NCIT_P106 "Organic Chemical" @default.
- NCIT_C185281 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C185281 NCIT_P107 "Intrathecal Deferoxamine" @default.
- NCIT_C185281 NCIT_P108 "Intrathecal Deferoxamine" @default.
- NCIT_C185281 NCIT_P208 "CL1773375" @default.
- NCIT_C185281 NCIT_P322 "CTRP" @default.
- NCIT_C185281 NCIT_P322 "GDC" @default.
- NCIT_C185281 NCIT_P399 "809199" @default.
- NCIT_C185281 normalizedInformationContent "100" @default.
- NCIT_C185281 referenceCount "1" @default.
- NCIT_C185281 hasExactSynonym "IT Deferoxamine" @default.
- NCIT_C185281 hasExactSynonym "IT Desferrioxamine" @default.
- NCIT_C185281 hasExactSynonym "IT-DFO" @default.
- NCIT_C185281 hasExactSynonym "Intrathecal Deferoxamine" @default.
- NCIT_C185281 inSubset NCIT_C116977 @default.
- NCIT_C185281 inSubset NCIT_C116978 @default.
- NCIT_C185281 inSubset NCIT_C128784 @default.
- NCIT_C185281 inSubset NCIT_C157711 @default.
- NCIT_C185281 inSubset NCIT_C157712 @default.
- NCIT_C185281 inSubset NCIT_C176424 @default.
- NCIT_C185281 type Class @default.
- NCIT_C185281 isDefinedBy ncit.owl @default.
- NCIT_C185281 label "Intrathecal Deferoxamine" @default.
- NCIT_C185281 subClassOf NCIT_C185281 @default.
- NCIT_C185281 subClassOf NCIT_C1908 @default.
- NCIT_C185281 subClassOf NCIT_C1932 @default.
- NCIT_C185281 subClassOf NCIT_C360 @default.