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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1855> ?p ?o ?g. }

• NCIT_C1855 IAO_0000115 "An anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR), which may result in inhibition of tyrosine kinase-dependent tumor growth. Specifically, this agent competes with the binding of ATP to the tyrosine kinase domain of EGFR, thereby inhibiting receptor autophosphorylation and resulting in inhibition of signal transduction. Gefitinib may also induce cell cycle arrest and inhibit angiogenesis. (NCI04)" @default.
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• NCIT_C1855 NCIT_NHC0 "C1855" @default.
• NCIT_C1855 NCIT_P106 "Organic Chemical" @default.
• NCIT_C1855 NCIT_P106 "Pharmacologic Substance" @default.
• NCIT_C1855 NCIT_P107 "Gefitinib" @default.
• NCIT_C1855 NCIT_P108 "Gefitinib" @default.
• NCIT_C1855 NCIT_P175 "715055" @default.
• NCIT_C1855 NCIT_P207 "C1122962" @default.
• NCIT_C1855 NCIT_P210 "184475-35-2" @default.
• NCIT_C1855 NCIT_P302 "Non-Small Cell Lung Carcinoma" @default.
• NCIT_C1855 NCIT_P319 "S65743JHBS" @default.
• NCIT_C1855 NCIT_P322 "CTRP" @default.
• NCIT_C1855 NCIT_P322 "FDA" @default.
• NCIT_C1855 NCIT_P322 "GDC" @default.
• NCIT_C1855 NCIT_P325 "A drug that is used to treat certain types of non-small cell lung cancer and is being studied in the treatment of other types of cancer. It is a type of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor." @default.
• NCIT_C1855 NCIT_P329 "43649" @default.
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• NCIT_C1855 NCIT_P350 "C22H24ClFN4O3" @default.
• NCIT_C1855 NCIT_P366 "Gefitinib" @default.
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• NCIT_C1855 NCIT_P399 "43649" @default.
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• NCIT_C1855 normalizedInformationContent "78.44064696698068" @default.
• NCIT_C1855 referenceCount "26" @default.
• NCIT_C1855 hasExactSynonym "4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline" @default.
• NCIT_C1855 hasExactSynonym "GEFITINIB" @default.
• NCIT_C1855 hasExactSynonym "Gefitinib" @default.
• NCIT_C1855 hasExactSynonym "Iressa" @default.
• NCIT_C1855 hasExactSynonym "N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholin) propoxy]-4-quinazolinamine" @default.
• NCIT_C1855 hasExactSynonym "ZD 1839" @default.
• NCIT_C1855 hasExactSynonym "ZD1839" @default.
• NCIT_C1855 hasExactSynonym "gefitinib" @default.
• NCIT_C1855 inSubset NCIT_C116977 @default.
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• NCIT_C1855 inSubset NCIT_C63923 @default.
• NCIT_C1855 type Class @default.
• NCIT_C1855 isDefinedBy ncit.owl @default.
• NCIT_C1855 label "Gefitinib" @default.
• NCIT_C1855 subClassOf B29040791037c62c6fb98d667ceee3371 @default.
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• NCIT_C1855 subClassOf NCIT_C163758 @default.
• NCIT_C1855 subClassOf NCIT_C163952 @default.
• NCIT_C1855 subClassOf NCIT_C1855 @default.
• NCIT_C1855 subClassOf NCIT_C1908 @default.

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