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- NCIT_C186366 IAO_0000115 "A bispecific antibody and novel T cell engager1 (nTCE) targeting both the tumor-associated antigen (TAA) CD20 and the CD3, a T-cell surface antigen, with potential immunomodulating and antineoplastic activities. Upon administration, anti-cd20/anti-cd3 bispecific antibody CM355 binds to both T-cells and CD20-expressing B-lineage tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against the CD20-expressing tumor B-cells. CD20 is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies." @default.
- NCIT_C186366 NCIT_A7 NCIT_C38896 @default.
- NCIT_C186366 NCIT_NHC0 "C186366" @default.
- NCIT_C186366 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C186366 NCIT_P108 "Anti-CD20/anti-CD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 NCIT_P208 "CL1778584" @default.
- NCIT_C186366 NCIT_P322 "GDC" @default.
- NCIT_C186366 NCIT_P399 "809065" @default.
- NCIT_C186366 NCIT_R124 NCIT_C17710 @default.
- NCIT_C186366 NCIT_R124 NCIT_C17828 @default.
- NCIT_C186366 NCIT_R124 NCIT_C18219 @default.
- NCIT_C186366 NCIT_R124 NCIT_C19986 @default.
- NCIT_C186366 NCIT_R124 NCIT_C40474 @default.
- NCIT_C186366 normalizedInformationContent "100" @default.
- NCIT_C186366 referenceCount "1" @default.
- NCIT_C186366 hasExactSynonym "Anti-CD20/CD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 hasExactSynonym "Anti-CD20/anti-CD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 hasExactSynonym "CD20/CD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 hasExactSynonym "CD20xCD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 hasExactSynonym "CM 355" @default.
- NCIT_C186366 hasExactSynonym "CM-355" @default.
- NCIT_C186366 hasExactSynonym "CM355" @default.
- NCIT_C186366 inSubset NCIT_C128784 @default.
- NCIT_C186366 inSubset NCIT_C157711 @default.
- NCIT_C186366 inSubset NCIT_C157712 @default.
- NCIT_C186366 inSubset NCIT_C176424 @default.
- NCIT_C186366 type Class @default.
- NCIT_C186366 isDefinedBy ncit.owl @default.
- NCIT_C186366 label "Anti-CD20/anti-CD3 Bispecific Antibody CM355" @default.
- NCIT_C186366 subClassOf NCIT_C112883 @default.
- NCIT_C186366 subClassOf NCIT_C129821 @default.
- NCIT_C186366 subClassOf NCIT_C129822 @default.
- NCIT_C186366 subClassOf NCIT_C141215 @default.
- NCIT_C186366 subClassOf NCIT_C1454 @default.
- NCIT_C186366 subClassOf NCIT_C163758 @default.
- NCIT_C186366 subClassOf NCIT_C164034 @default.
- NCIT_C186366 subClassOf NCIT_C186366 @default.
- NCIT_C186366 subClassOf NCIT_C1908 @default.
- NCIT_C186366 subClassOf NCIT_C1909 @default.
- NCIT_C186366 subClassOf NCIT_C200711 @default.
- NCIT_C186366 subClassOf NCIT_C201282 @default.
- NCIT_C186366 subClassOf NCIT_C20401 @default.
- NCIT_C186366 subClassOf NCIT_C274 @default.
- NCIT_C186366 subClassOf NCIT_C28227 @default.
- NCIT_C186366 subClassOf NCIT_C307 @default.
- NCIT_C186366 subClassOf NCIT_C308 @default.