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- NCIT_C186666 IAO_0000115 "A preparation of autologous T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) directed against the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon intravenous administration, the autologous anti-CD7 CAR T-cells PA3-17 specifically recognize and bind to CD7-expressing tumor cells, resulting in specific T-cell-mediated tumor cell lysis. CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas." @default.
- NCIT_C186666 NCIT_NHC0 "C186666" @default.
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- NCIT_C186666 NCIT_P108 "Autologous Anti-CD7 CAR T Cells PA3-17" @default.
- NCIT_C186666 NCIT_P208 "CL1779167" @default.
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- NCIT_C186666 normalizedInformationContent "100" @default.
- NCIT_C186666 referenceCount "1" @default.
- NCIT_C186666 hasExactSynonym "Autologous Anti-CD7 CAR T Cells PA3-17" @default.
- NCIT_C186666 hasExactSynonym "Autologous CD7-CAR T-cells PA3-17" @default.
- NCIT_C186666 hasExactSynonym "Autologous CD7-CAR-T Cells PA3-17" @default.
- NCIT_C186666 hasExactSynonym "Autologous CD7-targeted CAR-T Cells PA3-17" @default.
- NCIT_C186666 hasExactSynonym "PA3 17" @default.
- NCIT_C186666 hasExactSynonym "PA3-17" @default.
- NCIT_C186666 hasExactSynonym "PA317" @default.
- NCIT_C186666 inSubset NCIT_C128784 @default.
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- NCIT_C186666 type Class @default.
- NCIT_C186666 isDefinedBy ncit.owl @default.
- NCIT_C186666 label "Autologous Anti-CD7 CAR T Cells PA3-17" @default.
- NCIT_C186666 subClassOf NCIT_C129820 @default.
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