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- NCIT_C186728 IAO_0000115 "A preparation of human T-lymphocytes engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigens (TAAs) cluster of differentiation 19 (CD19), CD20 and CD22, with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CD19/CD20/CD22 CAR-T cells target and bind to CD19, CD20 and CD22 expressed on the surface of certain tumor cells. This induces selective toxicity in tumor cells expressing these TAAs. The TAAs are overexpressed in certain hematologic malignancies." @default.
- NCIT_C186728 NCIT_A7 NCIT_C17279 @default.
- NCIT_C186728 NCIT_A7 NCIT_C38894 @default.
- NCIT_C186728 NCIT_A7 NCIT_C38896 @default.
- NCIT_C186728 NCIT_NHC0 "C186728" @default.
- NCIT_C186728 NCIT_P106 "Cell" @default.
- NCIT_C186728 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C186728 NCIT_P107 "Anti-CD19/CD20/CD22 CAR T-Cells" @default.
- NCIT_C186728 NCIT_P108 "Anti-CD19/CD20/CD22 CAR T-Cells" @default.
- NCIT_C186728 NCIT_P208 "CL1779121" @default.
- NCIT_C186728 NCIT_P322 "CTRP" @default.
- NCIT_C186728 NCIT_P399 "809885" @default.
- NCIT_C186728 normalizedInformationContent "100" @default.
- NCIT_C186728 referenceCount "1" @default.
- NCIT_C186728 hasExactSynonym "Anti-CD19/20/22 Chimeric Antigen Receptor T-Cells" @default.
- NCIT_C186728 hasExactSynonym "Anti-CD19/CD20/CD22 CAR T-Cells" @default.
- NCIT_C186728 hasExactSynonym "CD19/CD20/CD22-targeted CAR-T Cells" @default.
- NCIT_C186728 inSubset NCIT_C116977 @default.
- NCIT_C186728 inSubset NCIT_C116978 @default.
- NCIT_C186728 inSubset NCIT_C128784 @default.
- NCIT_C186728 inSubset NCIT_C176424 @default.
- NCIT_C186728 type Class @default.
- NCIT_C186728 isDefinedBy ncit.owl @default.
- NCIT_C186728 label "Anti-CD19/CD20/CD22 CAR T-Cells" @default.
- NCIT_C186728 subClassOf NCIT_C129820 @default.
- NCIT_C186728 subClassOf NCIT_C129821 @default.
- NCIT_C186728 subClassOf NCIT_C129826 @default.
- NCIT_C186728 subClassOf NCIT_C137999 @default.
- NCIT_C186728 subClassOf NCIT_C142078 @default.
- NCIT_C186728 subClassOf NCIT_C154231 @default.
- NCIT_C186728 subClassOf NCIT_C176018 @default.
- NCIT_C186728 subClassOf NCIT_C186728 @default.
- NCIT_C186728 subClassOf NCIT_C1908 @default.
- NCIT_C186728 subClassOf NCIT_C1909 @default.
- NCIT_C186728 subClassOf NCIT_C1962 @default.
- NCIT_C186728 subClassOf NCIT_C201173 @default.
- NCIT_C186728 subClassOf NCIT_C201174 @default.
- NCIT_C186728 subClassOf NCIT_C274 @default.
- NCIT_C186728 subClassOf NCIT_C307 @default.
- NCIT_C186728 subClassOf NCIT_C308 @default.