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- NCIT_C187085 IAO_0000115 "A proenzyme and recombinant form of single-chain human urokinase plasminogen activator (scuPA), with potential intrapleural fibrinolytic and draining-promoting activities in certain lung conditions such as complicated parapneumonic pleural effusion (CPE) and empyema. After intrapleural administration, nasaruplase gamma is converted into uPA. uPA breaks down the fibrinous adhesions and promotes the draining of pleural fluid around the lungs in non-draining loculated pleural effusions (LPE). This may reduce LPE-associated complications, such as pain, shortness of breath, pleural infections, and sepsis." @default.
- NCIT_C187085 NCIT_NHC0 "C187085" @default.
- NCIT_C187085 NCIT_P106 "Enzyme" @default.
- NCIT_C187085 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C187085 NCIT_P107 "Nasaruplase Gamma" @default.
- NCIT_C187085 NCIT_P108 "Nasaruplase Gamma" @default.
- NCIT_C187085 NCIT_P208 "CL1791998" @default.
- NCIT_C187085 NCIT_P210 "2647419-93-8" @default.
- NCIT_C187085 NCIT_P319 "66522BCB6P" @default.
- NCIT_C187085 NCIT_P322 "CTRP" @default.
- NCIT_C187085 NCIT_P322 "FDA" @default.
- NCIT_C187085 normalizedInformationContent "100" @default.
- NCIT_C187085 referenceCount "1" @default.
- NCIT_C187085 hasExactSynonym "LTI 01" @default.
- NCIT_C187085 hasExactSynonym "LTI-01" @default.
- NCIT_C187085 hasExactSynonym "LTI01" @default.
- NCIT_C187085 hasExactSynonym "NASARUPLASE GAMMA" @default.
- NCIT_C187085 hasExactSynonym "Nasaruplase Gamma" @default.
- NCIT_C187085 hasExactSynonym "Recombinant Single-chain Urokinase Plasminogen Activator LTI-01" @default.
- NCIT_C187085 hasExactSynonym "Zymogen LTI-01" @default.
- NCIT_C187085 hasExactSynonym "scuPA LTI-01" @default.
- NCIT_C187085 inSubset NCIT_C116977 @default.
- NCIT_C187085 inSubset NCIT_C116978 @default.
- NCIT_C187085 inSubset NCIT_C128784 @default.
- NCIT_C187085 inSubset NCIT_C176424 @default.
- NCIT_C187085 inSubset NCIT_C63923 @default.
- NCIT_C187085 type Class @default.
- NCIT_C187085 isDefinedBy ncit.owl @default.
- NCIT_C187085 label "Nasaruplase Gamma" @default.
- NCIT_C187085 subClassOf NCIT_C187085 @default.
- NCIT_C187085 subClassOf NCIT_C1908 @default.
- NCIT_C187085 subClassOf NCIT_C1909 @default.
- NCIT_C187085 subClassOf NCIT_C29726 @default.
- NCIT_C187085 subClassOf NCIT_C307 @default.
- NCIT_C187085 subClassOf NCIT_C78273 @default.