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- NCIT_C1872 IAO_0000115 "A synthetic indolocarbazole multikinase inhibitor with potential antiangiogenic and antineoplastic activities. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors." @default.
- NCIT_C1872 NCIT_A24 NCIT_C274 @default.
- NCIT_C1872 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1872 NCIT_A7 NCIT_C17017 @default.
- NCIT_C1872 NCIT_A7 NCIT_C17322 @default.
- NCIT_C1872 NCIT_A7 NCIT_C17328 @default.
- NCIT_C1872 NCIT_A7 NCIT_C26202 @default.
- NCIT_C1872 NCIT_A7 NCIT_C28496 @default.
- NCIT_C1872 NCIT_NHC0 "C1872" @default.
- NCIT_C1872 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1872 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1872 NCIT_P107 "Midostaurin" @default.
- NCIT_C1872 NCIT_P108 "Midostaurin" @default.
- NCIT_C1872 NCIT_P207 "C0526371" @default.
- NCIT_C1872 NCIT_P210 "120685-11-2" @default.
- NCIT_C1872 NCIT_P302 "acute myeloid leukemia (AML) who are FLT3 mutation-positive (FLT3+)" @default.
- NCIT_C1872 NCIT_P319 "ID912S5VON" @default.
- NCIT_C1872 NCIT_P322 "CTRP" @default.
- NCIT_C1872 NCIT_P322 "FDA" @default.
- NCIT_C1872 NCIT_P322 "GDC" @default.
- NCIT_C1872 NCIT_P322 "PCDC" @default.
- NCIT_C1872 NCIT_P325 "A substance that is being studied in the treatment of leukemia. It belongs to the family of drugs called protein kinase inhibitors." @default.
- NCIT_C1872 NCIT_P329 "462346" @default.
- NCIT_C1872 NCIT_P330 "462346" @default.
- NCIT_C1872 NCIT_P350 "C35H30N4O4" @default.
- NCIT_C1872 NCIT_P366 "Midostaurin" @default.
- NCIT_C1872 NCIT_P368 "CHEBI:63452" @default.
- NCIT_C1872 NCIT_P375 "Midostaurin" @default.
- NCIT_C1872 NCIT_P399 "462346" @default.
- NCIT_C1872 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C1872 referenceCount "4" @default.
- NCIT_C1872 hasExactSynonym "CGP 41251" @default.
- NCIT_C1872 hasExactSynonym "CGP41251" @default.
- NCIT_C1872 hasExactSynonym "MIDOSTAURIN" @default.
- NCIT_C1872 hasExactSynonym "Midostaurin" @default.
- NCIT_C1872 hasExactSynonym "N-Benzoyl-Staurosporine" @default.
- NCIT_C1872 hasExactSynonym "N-Benzoylstaurosporine" @default.
- NCIT_C1872 hasExactSynonym "N-benzoyl-staurosporine" @default.
- NCIT_C1872 hasExactSynonym "PKC-412" @default.
- NCIT_C1872 hasExactSynonym "PKC412" @default.
- NCIT_C1872 hasExactSynonym "Rydapt" @default.
- NCIT_C1872 hasExactSynonym "midostaurin" @default.
- NCIT_C1872 inSubset NCIT_C116977 @default.
- NCIT_C1872 inSubset NCIT_C116978 @default.
- NCIT_C1872 inSubset NCIT_C128784 @default.
- NCIT_C1872 inSubset NCIT_C157711 @default.
- NCIT_C1872 inSubset NCIT_C157712 @default.
- NCIT_C1872 inSubset NCIT_C173234 @default.
- NCIT_C1872 inSubset NCIT_C174019 @default.
- NCIT_C1872 inSubset NCIT_C176424 @default.
- NCIT_C1872 inSubset NCIT_C177537 @default.
- NCIT_C1872 inSubset NCIT_C63923 @default.
- NCIT_C1872 type Class @default.
- NCIT_C1872 isDefinedBy ncit.owl @default.
- NCIT_C1872 label "Midostaurin" @default.
- NCIT_C1872 subClassOf NCIT_C1404 @default.
- NCIT_C1872 subClassOf NCIT_C1742 @default.
- NCIT_C1872 subClassOf NCIT_C1872 @default.
- NCIT_C1872 subClassOf NCIT_C1908 @default.
- NCIT_C1872 subClassOf NCIT_C1909 @default.
- NCIT_C1872 subClassOf NCIT_C2089 @default.
- NCIT_C1872 subClassOf NCIT_C274 @default.
- NCIT_C1872 subClassOf NCIT_C471 @default.
- NCIT_C1872 subClassOf NCIT_C61074 @default.