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- NCIT_C187300 IAO_0000115 "A preparation of T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19 CAR T cells AT101 recognize and bind to CD19-expressing tumor cells, thereby inducing selective toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies." @default.
- NCIT_C187300 NCIT_A7 NCIT_C38894 @default.
- NCIT_C187300 NCIT_NHC0 "C187300" @default.
- NCIT_C187300 NCIT_P106 "Cell" @default.
- NCIT_C187300 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C187300 NCIT_P108 "Anti-CD19 CAR T Cells AT101" @default.
- NCIT_C187300 NCIT_P208 "CL1792247" @default.
- NCIT_C187300 NCIT_P322 "GDC" @default.
- NCIT_C187300 NCIT_P399 "809530" @default.
- NCIT_C187300 normalizedInformationContent "100" @default.
- NCIT_C187300 referenceCount "1" @default.
- NCIT_C187300 hasExactSynonym "AT 101" @default.
- NCIT_C187300 hasExactSynonym "AT-101" @default.
- NCIT_C187300 hasExactSynonym "AT101" @default.
- NCIT_C187300 hasExactSynonym "Anti-CD19 CAR T Cells AT101" @default.
- NCIT_C187300 hasExactSynonym "Anti-CD19 CAR T-cells AT101" @default.
- NCIT_C187300 hasExactSynonym "Anti-CD19 CAR-T Cells AT101" @default.
- NCIT_C187300 inSubset NCIT_C128784 @default.
- NCIT_C187300 inSubset NCIT_C157711 @default.
- NCIT_C187300 inSubset NCIT_C157712 @default.
- NCIT_C187300 inSubset NCIT_C176424 @default.
- NCIT_C187300 type Class @default.
- NCIT_C187300 isDefinedBy ncit.owl @default.
- NCIT_C187300 label "Anti-CD19 CAR T Cells AT101" @default.
- NCIT_C187300 subClassOf NCIT_C129820 @default.
- NCIT_C187300 subClassOf NCIT_C129821 @default.
- NCIT_C187300 subClassOf NCIT_C129826 @default.
- NCIT_C187300 subClassOf NCIT_C137999 @default.
- NCIT_C187300 subClassOf NCIT_C142078 @default.
- NCIT_C187300 subClassOf NCIT_C154231 @default.
- NCIT_C187300 subClassOf NCIT_C176018 @default.
- NCIT_C187300 subClassOf NCIT_C187300 @default.
- NCIT_C187300 subClassOf NCIT_C1908 @default.
- NCIT_C187300 subClassOf NCIT_C1909 @default.
- NCIT_C187300 subClassOf NCIT_C1962 @default.
- NCIT_C187300 subClassOf NCIT_C274 @default.
- NCIT_C187300 subClassOf NCIT_C307 @default.
- NCIT_C187300 subClassOf NCIT_C308 @default.