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- NCIT_C1874 IAO_0000115 "A nonsteroidal 2-phenyl indole and a selective estrogen receptor modulator (SERM) with potential antineoplastic activity. Pipendoxifene antagonizes binding of estradiol to estrogen receptor alpha (ER alpha), thereby inhibiting ER alpha-mediated gene expression, interfering with estrogen activity and inhibiting estrogen-stimulated growth in estrogen-dependent breast cancer. In addition, this agent also exerts intrinsic estrogenic activity depending on the tissue types." @default.
- NCIT_C1874 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1874 NCIT_NHC0 "C1874" @default.
- NCIT_C1874 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1874 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1874 NCIT_P108 "Pipendoxifene" @default.
- NCIT_C1874 NCIT_P207 "C0935699" @default.
- NCIT_C1874 NCIT_P210 "198480-55-6" @default.
- NCIT_C1874 NCIT_P319 "TPC5Q8496G" @default.
- NCIT_C1874 NCIT_P322 "FDA" @default.
- NCIT_C1874 NCIT_P322 "GDC" @default.
- NCIT_C1874 NCIT_P325 "A substance that is being studied as a treatment for cancer. It belongs to a family of drugs called antiestrogens." @default.
- NCIT_C1874 NCIT_P329 "38112" @default.
- NCIT_C1874 NCIT_P330 "38112" @default.
- NCIT_C1874 NCIT_P350 "C29H32N2O3" @default.
- NCIT_C1874 NCIT_P366 "ERA_923" @default.
- NCIT_C1874 NCIT_P375 "Pipendoxifene" @default.
- NCIT_C1874 NCIT_P399 "38112" @default.
- NCIT_C1874 normalizedInformationContent "100" @default.
- NCIT_C1874 referenceCount "1" @default.
- NCIT_C1874 hasExactSynonym "2-(4-Hydroxyphenyl)-3-methyl-1-[4-(2-piperidin-1-ylethoxy)benzyl]-1H-indol-5-ol Hydrochloride" @default.
- NCIT_C1874 hasExactSynonym "ERA 923" @default.
- NCIT_C1874 hasExactSynonym "ERA-923" @default.
- NCIT_C1874 hasExactSynonym "PIPENDOXIFENE" @default.
- NCIT_C1874 hasExactSynonym "Pipendoxifene" @default.
- NCIT_C1874 inSubset NCIT_C128784 @default.
- NCIT_C1874 inSubset NCIT_C157711 @default.
- NCIT_C1874 inSubset NCIT_C157712 @default.
- NCIT_C1874 inSubset NCIT_C176424 @default.
- NCIT_C1874 inSubset NCIT_C177537 @default.
- NCIT_C1874 inSubset NCIT_C63923 @default.
- NCIT_C1874 type Class @default.
- NCIT_C1874 isDefinedBy ncit.owl @default.
- NCIT_C1874 label "Pipendoxifene" @default.
- NCIT_C1874 subClassOf NCIT_C129818 @default.
- NCIT_C1874 subClassOf NCIT_C147908 @default.
- NCIT_C1874 subClassOf NCIT_C163758 @default.
- NCIT_C1874 subClassOf NCIT_C1821 @default.
- NCIT_C1874 subClassOf NCIT_C1874 @default.
- NCIT_C1874 subClassOf NCIT_C1892 @default.
- NCIT_C1874 subClassOf NCIT_C1908 @default.
- NCIT_C1874 subClassOf NCIT_C1909 @default.
- NCIT_C1874 subClassOf NCIT_C274 @default.
- NCIT_C1874 subClassOf NCIT_C481 @default.
- NCIT_C1874 subClassOf NCIT_C483 @default.
- NCIT_C1874 subClassOf NCIT_C547 @default.
- NCIT_C1874 subClassOf NCIT_C548 @default.