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- NCIT_C187649 IAO_0000115 "A preparation of human cytomegalovirus (CMV)-specific T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) specific for the human tumor associated antigen (TAA) CD19, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19-CAR CMV-specific T-lymphocytes recognize, bind to, and induce selective toxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies. The anti-CD19-CAR CMV-specific T-lymphocytes may potentially be expanded in vivo through CMV vaccination." @default.
- NCIT_C187649 NCIT_A7 NCIT_C38894 @default.
- NCIT_C187649 NCIT_NHC0 "C187649" @default.
- NCIT_C187649 NCIT_P106 "Cell" @default.
- NCIT_C187649 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C187649 NCIT_P107 "Anti-CD19-CAR CMV-specific T-lymphocytes" @default.
- NCIT_C187649 NCIT_P108 "Anti-CD19-CAR CMV-specific T-lymphocytes" @default.
- NCIT_C187649 NCIT_P208 "CL1792418" @default.
- NCIT_C187649 NCIT_P322 "CTRP" @default.
- NCIT_C187649 NCIT_P399 "810184" @default.
- NCIT_C187649 normalizedInformationContent "100" @default.
- NCIT_C187649 referenceCount "1" @default.
- NCIT_C187649 hasExactSynonym "Anti-CD19-CAR CMV-specific T-cells" @default.
- NCIT_C187649 hasExactSynonym "Anti-CD19-CAR CMV-specific T-lymphocytes" @default.
- NCIT_C187649 hasExactSynonym "CMV-specific CD19 CAR-T Cells" @default.
- NCIT_C187649 hasExactSynonym "CMV-specific CD19-CAR T Cells" @default.
- NCIT_C187649 inSubset NCIT_C116977 @default.
- NCIT_C187649 inSubset NCIT_C116978 @default.
- NCIT_C187649 inSubset NCIT_C128784 @default.
- NCIT_C187649 inSubset NCIT_C176424 @default.
- NCIT_C187649 type Class @default.
- NCIT_C187649 isDefinedBy ncit.owl @default.
- NCIT_C187649 label "Anti-CD19-CAR CMV-specific T-lymphocytes" @default.
- NCIT_C187649 subClassOf NCIT_C129820 @default.
- NCIT_C187649 subClassOf NCIT_C129821 @default.
- NCIT_C187649 subClassOf NCIT_C129826 @default.
- NCIT_C187649 subClassOf NCIT_C137999 @default.
- NCIT_C187649 subClassOf NCIT_C142078 @default.
- NCIT_C187649 subClassOf NCIT_C154231 @default.
- NCIT_C187649 subClassOf NCIT_C176018 @default.
- NCIT_C187649 subClassOf NCIT_C187649 @default.
- NCIT_C187649 subClassOf NCIT_C1908 @default.
- NCIT_C187649 subClassOf NCIT_C1909 @default.
- NCIT_C187649 subClassOf NCIT_C1962 @default.
- NCIT_C187649 subClassOf NCIT_C274 @default.
- NCIT_C187649 subClassOf NCIT_C307 @default.
- NCIT_C187649 subClassOf NCIT_C308 @default.