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- NCIT_C1880 IAO_0000115 "The hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents." @default.
- NCIT_C1880 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1880 NCIT_A6 NCIT_C77588 @default.
- NCIT_C1880 NCIT_A7 NCIT_C17068 @default.
- NCIT_C1880 NCIT_A7 NCIT_C17319 @default.
- NCIT_C1880 NCIT_A7 NCIT_C17685 @default.
- NCIT_C1880 NCIT_A7 NCIT_C18490 @default.
- NCIT_C1880 NCIT_NHC0 "C1880" @default.
- NCIT_C1880 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1880 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1880 NCIT_P107 "Canertinib Dihydrochloride" @default.
- NCIT_C1880 NCIT_P108 "Canertinib Dihydrochloride" @default.
- NCIT_C1880 NCIT_P207 "C1707132" @default.
- NCIT_C1880 NCIT_P210 "289499-45-2" @default.
- NCIT_C1880 NCIT_P319 "ICJ93X8X90" @default.
- NCIT_C1880 NCIT_P322 "CTRP" @default.
- NCIT_C1880 NCIT_P322 "FDA" @default.
- NCIT_C1880 NCIT_P322 "GDC" @default.
- NCIT_C1880 NCIT_P325 "A substance being studied in the treatment of some types of cancer. Canertinib blocks the action of proteins called epidermal growth factor receptors, and may cause cancer cells to die. It is a type of tyrosine kinase inhibitor." @default.
- NCIT_C1880 NCIT_P329 "38403" @default.
- NCIT_C1880 NCIT_P330 "38403" @default.
- NCIT_C1880 NCIT_P350 "C24H25ClFN5O3.2HCl" @default.
- NCIT_C1880 NCIT_P366 "CI-1033" @default.
- NCIT_C1880 NCIT_P375 "Canertinib Dihydrochloride" @default.
- NCIT_C1880 NCIT_P399 "38403" @default.
- NCIT_C1880 normalizedInformationContent "100" @default.
- NCIT_C1880 referenceCount "1" @default.
- NCIT_C1880 hasExactSynonym "CANERTINIB DIHYDROCHLORIDE" @default.
- NCIT_C1880 hasExactSynonym "CI-1033" @default.
- NCIT_C1880 hasExactSynonym "Canertinib Dihydrochloride" @default.
- NCIT_C1880 hasExactSynonym "N-[-4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide Dihydrochloride" @default.
- NCIT_C1880 hasExactSynonym "PD-0183805-002B" @default.
- NCIT_C1880 hasExactSynonym "PD183805" @default.
- NCIT_C1880 hasExactSynonym "canertinib dihydrochloride" @default.
- NCIT_C1880 hasExactSynonym "canertinib" @default.
- NCIT_C1880 inSubset NCIT_C116977 @default.
- NCIT_C1880 inSubset NCIT_C116978 @default.
- NCIT_C1880 inSubset NCIT_C128784 @default.
- NCIT_C1880 inSubset NCIT_C157711 @default.
- NCIT_C1880 inSubset NCIT_C157712 @default.
- NCIT_C1880 inSubset NCIT_C176424 @default.
- NCIT_C1880 inSubset NCIT_C177537 @default.
- NCIT_C1880 inSubset NCIT_C63923 @default.
- NCIT_C1880 type Class @default.
- NCIT_C1880 isDefinedBy ncit.owl @default.
- NCIT_C1880 label "Canertinib Dihydrochloride" @default.
- NCIT_C1880 subClassOf NCIT_C129824 @default.
- NCIT_C1880 subClassOf NCIT_C129825 @default.
- NCIT_C1880 subClassOf NCIT_C1404 @default.
- NCIT_C1880 subClassOf NCIT_C163758 @default.
- NCIT_C1880 subClassOf NCIT_C163952 @default.
- NCIT_C1880 subClassOf NCIT_C1880 @default.
- NCIT_C1880 subClassOf NCIT_C1908 @default.
- NCIT_C1880 subClassOf NCIT_C1909 @default.
- NCIT_C1880 subClassOf NCIT_C1967 @default.
- NCIT_C1880 subClassOf NCIT_C2167 @default.
- NCIT_C1880 subClassOf NCIT_C2189 @default.
- NCIT_C1880 subClassOf NCIT_C274 @default.
- NCIT_C1880 subClassOf NCIT_C471 @default.