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- NCIT_C188312 IAO_0000115 "A bispecific antibody directed against both the tumor-associated antigen (TAA) CD19 and the co-stimulatory T-cell-specific surface glycoprotein CD28, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19/CD28 bispecific antibody RO7443904 targets and binds to both CD28 expressed on T-cells and CD19 expressed on tumor cells, which crosslinks the T-cells to the tumor cells. This may result in a potent cytotoxic T-lymphocyte (CTL) response against the CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies." @default.
- NCIT_C188312 NCIT_A7 NCIT_C38894 @default.
- NCIT_C188312 NCIT_NHC0 "C188312" @default.
- NCIT_C188312 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C188312 NCIT_P107 "Anti-CD19/CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 NCIT_P108 "Anti-CD19/CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 NCIT_P208 "CL1793029" @default.
- NCIT_C188312 NCIT_P322 "CTRP" @default.
- NCIT_C188312 NCIT_P322 "GDC" @default.
- NCIT_C188312 NCIT_P399 "810238" @default.
- NCIT_C188312 NCIT_R124 NCIT_C17710 @default.
- NCIT_C188312 NCIT_R124 NCIT_C17828 @default.
- NCIT_C188312 NCIT_R124 NCIT_C18219 @default.
- NCIT_C188312 NCIT_R124 NCIT_C19986 @default.
- NCIT_C188312 NCIT_R124 NCIT_C40474 @default.
- NCIT_C188312 normalizedInformationContent "100" @default.
- NCIT_C188312 referenceCount "1" @default.
- NCIT_C188312 hasExactSynonym "Anti-CD19/Anti-CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 hasExactSynonym "Anti-CD19/CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 hasExactSynonym "Anti-CD28/Anti-CD19 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 hasExactSynonym "CD19 x CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 hasExactSynonym "RG 6333" @default.
- NCIT_C188312 hasExactSynonym "RG-6333" @default.
- NCIT_C188312 hasExactSynonym "RG6333" @default.
- NCIT_C188312 hasExactSynonym "RO 7443904" @default.
- NCIT_C188312 hasExactSynonym "RO-7443904" @default.
- NCIT_C188312 hasExactSynonym "RO7443904" @default.
- NCIT_C188312 inSubset NCIT_C116977 @default.
- NCIT_C188312 inSubset NCIT_C116978 @default.
- NCIT_C188312 inSubset NCIT_C128784 @default.
- NCIT_C188312 inSubset NCIT_C157711 @default.
- NCIT_C188312 inSubset NCIT_C157712 @default.
- NCIT_C188312 inSubset NCIT_C176424 @default.
- NCIT_C188312 type Class @default.
- NCIT_C188312 isDefinedBy ncit.owl @default.
- NCIT_C188312 label "Anti-CD19/CD28 Bispecific Antibody RO7443904" @default.
- NCIT_C188312 subClassOf NCIT_C112889 @default.
- NCIT_C188312 subClassOf NCIT_C129820 @default.
- NCIT_C188312 subClassOf NCIT_C129821 @default.
- NCIT_C188312 subClassOf NCIT_C129822 @default.
- NCIT_C188312 subClassOf NCIT_C1454 @default.
- NCIT_C188312 subClassOf NCIT_C163758 @default.
- NCIT_C188312 subClassOf NCIT_C188312 @default.
- NCIT_C188312 subClassOf NCIT_C1908 @default.
- NCIT_C188312 subClassOf NCIT_C1909 @default.
- NCIT_C188312 subClassOf NCIT_C198634 @default.
- NCIT_C188312 subClassOf NCIT_C20401 @default.
- NCIT_C188312 subClassOf NCIT_C274 @default.
- NCIT_C188312 subClassOf NCIT_C28227 @default.
- NCIT_C188312 subClassOf NCIT_C307 @default.
- NCIT_C188312 subClassOf NCIT_C308 @default.