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- NCIT_C189803 IAO_0000115 "A bivalent booster vaccine consisting of elasomeran, a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding the prefusion stabilized spike (S) protein of the SARS-CoV-2 Wuhan-Hu-1 strain (original), and imelasomeran, a LNP encapsulating mRNA encoding the prefusion stabilized S-protein of the SARS-CoV-2 Omicron variant B.1.1.529, with potential immunizing activity against SARS-CoV-2. Upon administration of elasomeran/imelasomeran, the LNP binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection." @default.
- NCIT_C189803 NCIT_NHC0 "C189803" @default.
- NCIT_C189803 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C189803 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C189803 NCIT_P108 "Elasomeran/Imelasomeran" @default.
- NCIT_C189803 NCIT_P208 "CL1798631" @default.
- NCIT_C189803 normalizedInformationContent "100" @default.
- NCIT_C189803 referenceCount "1" @default.
- NCIT_C189803 hasExactSynonym "Elasomeran/Imelasomeran" @default.
- NCIT_C189803 hasExactSynonym "Original/Omicron BA.1 Bivalent COVID-19 Booster Vaccine mRNA-1273.214" @default.
- NCIT_C189803 hasExactSynonym "mRNA 1273.214" @default.
- NCIT_C189803 hasExactSynonym "mRNA-1273.214" @default.
- NCIT_C189803 hasExactSynonym "mRNA1273.214" @default.
- NCIT_C189803 inSubset NCIT_C173381 @default.
- NCIT_C189803 inSubset NCIT_C173383 @default.
- NCIT_C189803 type Class @default.
- NCIT_C189803 isDefinedBy ncit.owl @default.
- NCIT_C189803 label "Elasomeran/Imelasomeran" @default.
- NCIT_C189803 subClassOf NCIT_C1572 @default.
- NCIT_C189803 subClassOf NCIT_C172787 @default.
- NCIT_C189803 subClassOf NCIT_C173023 @default.
- NCIT_C189803 subClassOf NCIT_C181140 @default.
- NCIT_C189803 subClassOf NCIT_C189803 @default.
- NCIT_C189803 subClassOf NCIT_C1908 @default.
- NCIT_C189803 subClassOf NCIT_C1909 @default.
- NCIT_C189803 subClassOf NCIT_C307 @default.
- NCIT_C189803 subClassOf NCIT_C308 @default.
- NCIT_C189803 subClassOf NCIT_C923 @default.
- NCIT_C189803 subClassOf NCIT_C96404 @default.