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- NCIT_C189804 IAO_0000115 "A bivalent booster vaccine consisting of elasomeran, a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding the prefusion stabilized spike (S) protein of the SARS-CoV-2 Wuhan-Hu-1 strain (original), and davesomeran, a LNP encapsulating mRNA encoding the prefusion stabilized S-protein of the SARS-CoV-2 Omicron variant lineages BA.4 and BA.5 (Omicron BA.4/BA.5), with potential immunizing activity against SARS-CoV-2. Upon administration of elasomeran/davesomeran, the LNPs bind to the plasma membrane of cells and release the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection." @default.
- NCIT_C189804 NCIT_NHC0 "C189804" @default.
- NCIT_C189804 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C189804 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C189804 NCIT_P108 "Elasomeran/Davesomeran" @default.
- NCIT_C189804 NCIT_P208 "CL1798634" @default.
- NCIT_C189804 NCIT_P322 "SeroNet" @default.
- NCIT_C189804 normalizedInformationContent "100" @default.
- NCIT_C189804 referenceCount "1" @default.
- NCIT_C189804 hasExactSynonym "COVID-19 Bivalent Vaccine mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "Elasomeran/Davesomeran" @default.
- NCIT_C189804 hasExactSynonym "Elasomeran/LNP-encapsulated mRNA-based Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "LNP-encapsulated mRNA-based Original and Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "Lipid Nanoparticle-encapsulated mRNA-based Original and Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "Moderna COVID-19 Vaccine, Bivalent, US" @default.
- NCIT_C189804 hasExactSynonym "Original/Omicron BA.4/BA.5 Bivalent COVID-19 Booster Vaccine mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "mRNA 1273.222" @default.
- NCIT_C189804 hasExactSynonym "mRNA-1273.222" @default.
- NCIT_C189804 hasExactSynonym "mRNA1273.222" @default.
- NCIT_C189804 inSubset NCIT_C173381 @default.
- NCIT_C189804 inSubset NCIT_C173383 @default.
- NCIT_C189804 inSubset NCIT_C179027 @default.
- NCIT_C189804 inSubset NCIT_C189083 @default.
- NCIT_C189804 type Class @default.
- NCIT_C189804 isDefinedBy ncit.owl @default.
- NCIT_C189804 label "Elasomeran/Davesomeran" @default.
- NCIT_C189804 subClassOf NCIT_C1572 @default.
- NCIT_C189804 subClassOf NCIT_C172787 @default.
- NCIT_C189804 subClassOf NCIT_C173023 @default.
- NCIT_C189804 subClassOf NCIT_C181140 @default.
- NCIT_C189804 subClassOf NCIT_C189804 @default.
- NCIT_C189804 subClassOf NCIT_C1908 @default.
- NCIT_C189804 subClassOf NCIT_C1909 @default.
- NCIT_C189804 subClassOf NCIT_C307 @default.
- NCIT_C189804 subClassOf NCIT_C308 @default.
- NCIT_C189804 subClassOf NCIT_C923 @default.
- NCIT_C189804 subClassOf NCIT_C96404 @default.